931055

tBuXPhos Pd G3 ChemBeads

• Sinónimos: [(2-Di-tert-butylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)-2-(2′-amino-1,1′-biphenyl)] palladium(II) methanesulfonate, tBuXPhos-Pd-G3
• Fórmula empírica (notación de Hill): C₄₂H₅₈NO₃PPdS
• Número de CAS: 1447963-75-8
• Peso molecular: 794.37
• NACRES: NA.82

Propiedades

• Análisis: ~6 wt.% loading of catalyst
• Nivel de calidad: 100
• formulario: solid
• idoneidad de la reacción: reagent type: catalyst; reaction type: Cross Couplings
• Extensión del etiquetado: ~6 wt. % loading of catalyst
• cadena SMILES: O=S([O-][Pd+2]1(P(C(C)(C)C)(C(C)(C)C)C2=CC=CC=C2C3=C(C(C)C)C=C(C(C)C)C=C3C(C)C)[C-]4=C(C5=C(N1)C=CC=C5)C=CC=C4)(C)=O
• InChI: 1S/C29H45P.C12H10N.CH4O3S.Pd/c1-19(2)22-17-24(20(3)4)27(25(18-22)21(5)6)23-15-13-14-16-26(23)30(28(7,8)9)29(10,11)12;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h13-21H,1-12H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;;;+1/p-1
• Clave InChI: SQQOHCLJPLSJGX-UHFFFAOYSA-M

Descripción

Descripción general

tBuXPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. tBuXPhos Pd G3 is an excellent reagent for Buchwald-Hartwig cross-coupling reaction. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

For larger scale uses, product also available in powdered form (762229)

Aplicación

tBuXPhos Pd G3 may be used to synthesize 4-cyano-7-azaindole from 4-chloro-7-azaindole by cyanation reaction. It may also be used for the α-arylation reaction of acetate esters at room temperature.

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Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable