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Merck

910007

Sigma-Aldrich

20-Azido-3,6,9,12,15,18-hexaoxaicosanoic acid

95%

Sinónimos:

Azido-PEG6-CH2CO2H, Azido-PEG6-acid, N3-PEG6-CH2COOH

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About This Item

Fórmula empírica (notación de Hill):
C14H27N3O8
Número de CAS:
Peso molecular:
365.38
Código UNSPSC:
12352106

Análisis

95%

formulario

(Liquid or Semi-Solid or Paste or Solid)

idoneidad de la reacción

reaction type: click chemistry
reagent type: cross-linking reagent

grupo funcional

azide
carboxylic acid

temp. de almacenamiento

2-8°C

cadena SMILES

OC(COCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

Aplicación

This heterobifunctional, PEGylated crosslinker 20-Azido-3,6,9,12,15,18-hexaoxaicosanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG6-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

Información legal

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

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Descripción
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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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