QBD10512

Azido-dPEG^®₈-acid

• Sinónimos: Polyethylene glycol
• Fórmula empírica (notación de Hill): C₁₉H₃₇N₃O₁₀
• Número de CAS: 1214319-92-2
• Peso molecular: 467.51
• Número MDL: MFCD21363300
• Código UNSPSC: 12352106
• ID de la sustancia en PubChem: 329823934
• NACRES: NA.22

Propiedades

• Análisis: >90%
• formulario: solid or viscous liquid
• idoneidad de la reacción: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• grupo funcional: azide; carboxylic acid
• arquitectura del polímero: shape: linear; functionality: heterobifunctional
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• cadena SMILES: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

Descripción

Características y beneficios

The azido-dPEG^®₈ contains an azide function on one end of a single molecular weight dPEG^® spacer (32.2Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Información legal

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable