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675075

Sigma-Aldrich

8-Mercaptooctanoic acid

95%

Sinónimos:

8-Thiooctanoic acid, MOA

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About This Item

Fórmula empírica (notación de Hill):
C8H16O2S
Número de CAS:
74328-61-3
Peso molecular:
176.28
Número MDL:
MFCD08705279
Código UNSPSC:
12352103
ID de la sustancia en PubChem:
24885256
NACRES:
NA.23

254,00 €

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Ensayo

95%

índice de refracción

n20/D 1.4808

densidad

1.0326 g/mL at 25 °C

temp. de almacenamiento

−20°C

cadena SMILES

OC(=O)CCCCCCCS

InChI

1S/C8H16O2S/c9-8(10)6-4-2-1-3-5-7-11/h11H,1-7H2,(H,9,10)

Clave InChI

FYEMIKRWWMYBFG-UHFFFAOYSA-N

Categorías relacionadas

Descripción general

8-Mercaptooctanoic acid (MOA) is an carboxylic acid terminated alkanethiol that forms self-assembled monolayers (SAMs) that facilitate subsequent surface immobilization of other molecular species.[1]
8-mercaptooctanoic acid (MOA) forms a self-assembled monolayer (SAM) on the surface of nanoparticles. MOA consists of thiol and carboxylic groups which helps in the surface treatment of different nanoparticles.[2][3]

Aplicación

MOA is a used as a SAM for surface modification of gold electrodes for quartz crystal microbalance (QCMB) measurement.[2] It may be used as a monolayer that facilitates ferritin absorption on gold electrodes for uptake of excess iron in the cell.[3] It may also be used for preparation of nitric oxide based gold nanoparticles (NO-AuNPs) for macrophage photo-thermal therapy under NIR irradiation.[4]
MOA may form SAM that can be used in the surface modification of gold electrodes which are useful for the study of surface characteristics of ferritin.[3] It may also be used to form SAM with hydrophilic end groups to be used as a protective coating on the electrodes for efficient electron transport in semiconductor devices.[5]
This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized[6] to introduce more complex end groups. Can also be used to form a protective barrier monolayer to allow deposition of a passivating oxide layer.[7]

Otras notas

This product should be stored in the freezer, 0 to -20 °C

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319,H335

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificados de análisis (COA)

Lot/Batch Number
MKCW9605
MKCT4436
MKCS4446
MKCR0366
MKCP0347

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Nitric oxide-activatable gold nanoparticles for specific targeting and photo-thermal ablation of macrophages.
Park J, et al.
Chemical Communications (Cambridge, England), 53(81), 11229-11232 (2017)
Anna Paula V Moura et al.
ACS central science, 3(9), 1026-1031 (2017-10-06)
Secreted and surface-displayed carbohydrates are essential for virulence and viability of many parasites, including for immune system evasion. We have identified the α-Gal trisaccharide epitope on the surface of the protozoan parasites
Rosa Gueccia et al.
Membranes, 10(6) (2020-07-01)
Acid recovery from pickling waste solutions is an important step to enhance hot-dip-galvanizing industry process sustainability. Diffusion dialysis (DD) can be used to separate acids and heavy metals (e.g., iron and zinc) from pickling waters, promoting the circular use of
Linan Liu et al.
EBioMedicine, 47, 563-577 (2019-09-11)
This study aims to evaluate the quality of preclinical data, determine the effect sizes, and identify experimental measures that inform efficacy using mesenchymal stromal (or stem) cells (MSC) therapy in animal models of rheumatoid arthritis (RA). Literature searches were performed
Jonathan M G Perry
Anatomical record (Hoboken, N.J. : 2007), 301(2), 343-362 (2018-01-14)
The jaw adductor muscles of extinct mammals are often reconstructed to elucidate paleoecological relationships and to make broad comparisons among taxa. Muscle lever arms, bite load arms, muscle dimensions, and gape are often also reconstructed to better understand feeding. Several
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