In this report, the development of a new class of monocarboxylate functionalized cyanine derivatives using improved synthetic procedures is detailed. The employed synthetic strategy relies on efficient nucleophilic attack of alkyl-thiols on cyanine dyes bearing chloro-substituted polymethinic linkers. Monocarboxylate derivatized
Monofunctional near-infrared fluorochromes for imaging applications
Hilderbrand SA, et al.
Bioconjugate Chemistry, 16(5), 1275-1281 (2005)
Controlled assembly of plasmonic nanoparticles using neutral-charged diblock copolymers
Yin Q, et al.
Journal of Colloid and Interface Science, 431(5), 97-104 (2014)
International journal of pharmaceutics, 553(1-2), 169-185 (2018-10-16)
A dual-targeting drug delivery system for paclitaxel (PTX) was developed by functionalizing novel polyester-based nanoparticles (NPs) with peptides possessing special affinity for low-density lipoprotein receptor (LDLR), overcoming the limitations of the current chemotherapeutics, to transport drug from blood to brain
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