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467804

Sigma-Aldrich

Hydroxylamine solution

50 wt. % in H2O, 99.999%

Sinónimos:

HDA

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10 ML
36,60 €
50 ML
131,00 €

36,60 €

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10 ML
36,60 €
50 ML
131,00 €

About This Item

Fórmula lineal:
NH2OH
Número de CAS:
7803-49-8
Peso molecular:
33.03
Número CE:
232-259-2
Número MDL:
MFCD00044522
Código UNSPSC:
12352116
ID de la sustancia en PubChem:
24870439
NACRES:
NA.22

36,60 €

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Nivel de calidad

100

Ensayo

99.999%

concentración

50 wt. % in H2O

bp

107 °C

densidad

1.078 g/mL at 25 °C

cadena SMILES

NO

InChI

1S/H3NO/c1-2/h2H,1H2

Clave InChI

AVXURJPOCDRRFD-UHFFFAOYSA-N

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Descripción general

Hydroxylamine solution is widely used as a reducing agent and antioxidant in organic synthesis, polymer industry and water treatment.[1]

Aplicación

Hydroxylamine solution (NH2OH) can be used as a reactant for the preparation of:
  • Primary amides from aldehydes catalyzed by an arene–ruthenium(II) complex.[2]
  • Hydroxyaminoguanidines and carboxamide derivatives of ofloxacin for biological studies.[3][4]
  • Fe3O4/Au (GoldMag) nanoparticles for antibody immobilization.[5]

Reactant for preparation of:
  • Prodrug for cardiovascular agent Nω-hydroxy-L-arginine (NOHA, nitric oxide precursor)
  • Hydroxyaminoguanidines as anti-cancer agents
  • Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced phosphoenolpyruvate caboxykinase (PEPCK) transactivation
  • Carboxamide derivatives of ofloxacin with improved antimicrobial properties
  • Analogues of coumarin based TNF-α converting enzyme (TACE) inhibitors
  • HIV integrase inhibitors

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

Órganos de actuación

Blood, Respiratory system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificados de análisis (COA)

Lot/Batch Number
STBL4188
STBL1755
STBL1408
STBK6006
STBK9341

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The synthesis of GoldMag nano-particles and their application for antibody immobilization
Cui Y, et al.
Biomedical Microdevices, 7(2), 153-156 (2005)
Ruthenium-catalyzed one-pot synthesis of primary amides from aldehydes in water
Garcia-Alvarez R, et al.
Royal Society of Chemistry Advances, 3(17), 5889-5894 (2013)
Synthesis, characterization and biological activity of a series of carboxamide derivatives of ofloxacin
Arayne MS, et al.
Archives of Pharmacal Research, 33(12), 1901-1909 (2010)
Using hydroxylamine as a reducer to prepare N-doped graphene hydrogels used in high-performance energy storage
Chang, Yunzhen and Han, et al.
Journal of Power Sources, 238, 492-500 (2013)
N-Hydroxy-N′-aminoguanidines as anti-cancer lead molecule: QSAR, synthesis and biological evaluation
Basu A, et al.
Bioorganic & Medicinal Chemistry Letters, 21(11), 3324-3328 (2011)
Ver todos los artículos relacionados

Preguntas

1–3 de 3 Preguntas  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 respuesta

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 respuesta

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. Please provide the molarity for Product 467804?

    1 respuesta

    1. The molarity of a 50% solution for Product 467804 would be 15.1M. This is calculated based on the fact that 1M is equivalent to 33.03 g in 1L

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