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Merck

401633

Sigma-Aldrich

1-Pyrenemethylamine hydrochloride

95%

Sinónimos:

PMA

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About This Item

Fórmula empírica (notación de Hill):
C17H13N · HCl
Número de CAS:
Peso molecular:
267.75
Número MDL:
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
NACRES:
NA.22

Nivel de calidad

Análisis

95%

formulario

powder

mp

258 °C (dec.) (lit.)

cadena SMILES

Cl[H].NCc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C17H13N.ClH/c18-10-14-7-6-13-5-4-11-2-1-3-12-8-9-15(14)17(13)16(11)12;/h1-9H,10,18H2;1H

Clave InChI

RGNMXKKNDSHTFD-UHFFFAOYSA-N

Descripción general

1-Pyrenemethylamine hydrochloride is an organic building block.

Aplicación

1-Pyrenemethylamine (PyNH2) has also been used for the synthesis of:
  • Pyrenyl hyaluronan (Py-HA), a pyrenyl-based polymer that can be used for the development of pH-triggered drug carriers.
  • An electrochemical electrode of reduced graphene oxide bound with pyrene functionalized folic acid derivative.

It can also be used for the synthesis of 4,6-dichloro-2-pyrenemethylamine-1,3,5-triazine, a precursor to synthesize a star shaped polymer 4,6-bis(9H-carbazol-2-yloxy)-2-(pyrenemethylamine)-1,3,5 triazine (TPC).
1-Pyrenemethylamine hydrochloride (PyNH2) has been used for the loading of human telomerase reverse transcriptase (hTERT) small interfering RNA (siRNA) to the functionalized graphene oxide (GO) for the tumor targeting delivery of siRNA.
1-Pyrenemethylamine hydrochloride has been used in the preparation of 1-pyrenemethylamine. It may be used for the noncovalent functionalization of SWNTs with cationic moieties which binds strongly to the negatively charged phosphate backbone of the DNA. It may be used in the preparation of the following Schiff-base ligand:
  • pyren-1-ylmethyl-[2-(6-{2-[(pyren-1-ylmethylimino)-methyl]-phenoxymethyl}-pyridin-2-ylmethoxy)-benzylidene]-amine
  • 2(pyren-1-ylmethyl-{2-[6-(2-{[(pyren-1-ylmethyl)-amino]-methyl}- phenoxymethyl)-pyridin-2-ylmethoxy])-benzyl}-amine

Pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves


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Visite la Librería de documentos

Reactively formed block and graft copolymers as compatibilizers for polyamide 66/PS blends.
Jeon HK, et al.
Polymer, 45(1), 197-206 (2004)
Sudarat Yenjai et al.
Journal of photochemistry and photobiology. B, Biology, 173, 35-42 (2017-05-30)
A new photochemical reagent, succinic acid-1(1-pyrene)methylamide (PMA-SUC), was developed to recognize the specific binding sites on model proteins, egg-white lysozyme and avidin. The interaction of the photochemical reagent with the proteins was studied by UV-Vis, fluorescence spectroscopic methods and docking
Fabien Giroud et al.
Biosensors & bioelectronics, 87, 957-963 (2016-09-26)
We report the functionalization of multi-walled carbon nanotubes (MWCNTs) electrodes by a bifunctional nitroaromatic molecule accomplished via π-π interactions of a pyrene derivative. DTNB (5,5'-dithiobis(2-nitrobenzoic acid)) has the particularity to possess both electroactivable nitro groups and negatively charged carboxylic groups.
Liwei Hui et al.
ACS nano, 14(10), 13047-13055 (2020-10-14)
We demonstrate area-selective atomic layer deposition (ALD) of oxides on DNA nanostructures. Area-selective ALD of Al2O3, TiO2, and HfO2 was successfully achieved on both 2D and 3D DNA nanostructures deposited on a polystyrene (PS) substrate. The resulting DNA-inorganic hybrid structure
Assembly of chemically reduced graphene oxide with folic acid functionalized with pyrene moieties and electrochemical sensing of folate receptors.
Kwon B, et al.
Carbon Letters, 27(2), 26-34 (2018)

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