283754

2(5H)-Furanone

98%

• Sinónimos: γ-Crotonolactone, 2-Buten-1,4-olide
• Fórmula empírica (notación de Hill): C₄H₄O₂
• Número de CAS: 497-23-4
• Peso molecular: 84.07
• Beilstein: 383585
• Número CE: 207-839-3
• Número MDL: MFCD00005376
• Código UNSPSC: 12352100
• ID de la sustancia en PubChem: 24857130
• NACRES: NA.22

Propiedades

• Análisis: 98%
• formulario: liquid
• índice de refracción: n20/D 1.469 (lit.)
• bp: 86-87 °C/12 mmHg (lit.)
• mp: 4-5 °C (lit.)
• densidad: 1.185 g/mL at 25 °C (lit.)
• temp. de almacenamiento: 2-8°C
• cadena SMILES: O=C1OCC=C1
• InChI: 1S/C4H4O2/c5-4-2-1-3-6-4/h1-2H,3H2
• Clave InChI: VIHAEDVKXSOUAT-UHFFFAOYSA-N

Descripción

Descripción general

Chiral urea compounds catalyzed hetero-Michael addition reaction of 2(5H)-furanone (γ-crotonolactone) to pyrrolidine. The quorum sensing inhibition activity by 2(5H)-furanone was studied using bioindicator strains.

Aplicación

2(5H)-Furanone (γ-Crotonolactone) has been used in:

• synthesis of (+)-L-733,060, (+)-CP-99,994 and (2S,3R)-3-hydroxypipecolic acid
• synthesis of 5-substituted 2(5H) furanones (γ-butenolides) via direct aldol reaction with aromatic aldehydes catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts
• Michael addition reactions for synthesis of lignans
• three-component Michael-Aldol reactions with an aldehyde anda thiolate or carbanion

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 213.8 °F - closed cup
• Punto de inflamabilidad (°C): 101 °C - closed cup
• Equipo de protección personal: Eyeshields, Gloves, type ABEK (EN14387) respirator filter