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Merck

SOCS1

suppressor of cytokine signaling 1

Sinónimos:
CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
Especie:
ID UniProtKB:
ID del gen:
  • Human(8651) Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
  • Mouse(12703) suppressor of cytokine signaling 1
  • Rat(252971) suppressor of cytokine signaling 1
  • naked mole-rat(101729320) suppressor of cytokine signaling 1
  • domestic guinea pig(100728652) suppressor of cytokine signaling 1
  • cow(518795) suppressor of cytokine signaling 1
  • sheep(101107324) suppressor of cytokine signaling 1
  • dog(490006) suppressor of cytokine signaling 1
  • chicken(416630) suppressor of cytokine signaling 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SOCS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-SOCS1 antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
bovine, human, mouse, pig, rabbit, rat
Aplicación
immunohistochemistry
western blot
Anti-SOCS1 Antibody, clone 4H1, clone 4H1, Upstate®, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunoprecipitation (IP)
western blot
Anti-SOCS1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-SOCS1 Antibody, clone 5T6Z10, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SOCS1,
Especie
human
MISSION® esiRNA, targeting mouse Socs1,
Especie
mouse