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PSPC1

paraspeckle component 1

Sinónimos:
PSP1
Especie:
ID UniProtKB:
ID del gen:
  • Human(55269) Summary: This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified. [provided by RefSeq, Aug 2011]
  • Mouse(66645) paraspeckle protein 1
  • Rat(305910) paraspeckle component 1
  • Zebrafish(692285) paraspeckle component 1
  • chicken(418955) paraspeckle component 1
  • cow(506696) paraspeckle component 1
  • naked mole-rat(101714198) paraspeckle component 1
  • domestic guinea pig(100713500) paraspeckle component 1
  • sheep(101119830) paraspeckle component 1
  • domestic cat(101081777) paraspeckle component 1
  • dog(477347) paraspeckle component 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PSPC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-PSPC1 (N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-PSPC1 antibody, Mouse monoclonal, clone 1L4, purified from hybridoma cell culture,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
western blot
Anti-PSPC1 (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
immunoprecipitation (IP)

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PSPC1,
Especie
human
MISSION® esiRNA, targeting mouse Pspc1,
Especie
mouse