Saltar al contenido
Merck

GRIN2C

glutamate receptor, ionotropic, N-methyl D-aspartate 2C

Sinónimos:
GluN2C, NMDAR2C, NR2C
Especie:
ID UniProtKB:
ID del gen:
  • Human(2905) Summary: This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
  • Mouse(14813) glutamate receptor, ionotropic, NMDA2C (epsilon 3)
  • Rat(24411) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • domestic guinea pig(100721967) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • naked mole-rat(101698922) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • sheep(101102915) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • domestic cat(101091740) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • cow(535158) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • chicken(431090) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
  • dog(483302) glutamate receptor, ionotropic, N-methyl D-aspartate 2C

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Referencia del producto
Descripción
Especie
L-Tyrosine hydrochloride, ≥98% (TLC),
Especie
mouse, rat, human
D-Cycloserine, synthetic,
Especie
human
Dextromethorphan hydrobromide monohydrate, ≥99% (TLC),
Especie
human
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
Especie
human, rat
D-Cycloserine, ,
Especie
human, mouse, rat

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
(±)-Ketamine hydrochloride, solid,
Especie
human
S-(+)-Ketamine hydrochloride, ,
Especie
human
Ketamine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Acamprosate calcium, ≥98% (HPLC), powder,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
D(−)-2-Amino-5-phosphonopentanoic acid, NMDA receptor antagonist,
Especie
mouse, rat
Dextrorphan tartrate, powder,
Especie
human
Ifenprodil (+)-tartrate salt, ,
Especie
human
Arcaine sulfate salt, ,
Especie
human
(±)-2-Amino-4-phosphonobutyric acid, solid,
Especie
rat, human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GRIN2C antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anticuerpo anti-NMDAR2C, también reconoce las NMDAR2A y 2B, Chemicon®, from rabbit,
Reactividad de especies
rat
Aplicación
immunoprecipitation (IP)
western blot
Anti-Glutamate Receptor NMDAR2C (NR2C) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Especie
human
Agmatine sulfate salt, ≥97%, powder,
Especie
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Especie
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Pentamidine isethionate salt, powder,
Especie
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Especie
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GRIN2C,
Especie
human