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Merck

GFI1

growth factor independent 1 transcription repressor

Sinónimos:
GFI-1, GFI1A, SCN2, ZNF163
Especie:
ID UniProtKB:
ID del gen:
  • Human(2672) Summary: This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14581) growth factor independent 1
  • Rat(24388) growth factor independent 1 transcription repressor
  • domestic guinea pig(100716876) growth factor independent 1 transcription repressor
  • naked mole-rat(101715410) growth factor independent 1 transcription repressor
  • dog(490156) growth factor independent 1 transcription repressor
  • domestic cat(100127020) growth factor independent 1 transcription repressor
  • cow(100139952) growth factor independent 1 transcription repressor
  • sheep(101116880) growth factor independent 1 transcription repressor
  • chicken(429088) growth factor independent 1 transcription repressor

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-GFI1 antibody produced in mouse, clone 3G8, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-GFI1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, human, pig, rat
Aplicación
western blot
Anti-Growth Factor Independence-1 antibody, Mouse monoclonal, clone 2.5D.17, purified from hybridoma cell culture,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
microarray

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GFI1,
Especie
human