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Merck

GABRA1

gamma-aminobutyric acid (GABA) A receptor, alpha 1

Sinónimos:
ECA4, EJM, EJM5
Especie:
Human GABRA1 (2554), Mouse Gabra1 (14394), Rat Gabra1 (29705), domestic guinea pig Gabra1 (100721626), cow GABRA1 (780973), dog GABRA1 (489143), naked mole-rat Gabra1 (101719179), Zebrafish gabra1 (768183), sheep GABRA1 (101117759), chicken GABRA1 (374214)
ID UniProtKB:
P14867, D3DQK6, Q8N629
ID del gen:
  • Human(2554) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14394) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
  • Rat(29705) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • domestic guinea pig(100721626) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • cow(780973) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • dog(489143) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • naked mole-rat(101719179) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • Zebrafish(768183) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • sheep(101117759) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • chicken(374214) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • domestic cat(100286792) gamma-aminobutyric acid (GABA) A receptor, alpha 1

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Small Molecule - Agonist

Número de producto
Descripción
Especie
T101
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Especie
human
G019
Muscimol hydrobromide, ≥98% (HPLC), solid,
Especie
human
G002
Isoguvacine hydrochloride, solid,
Especie
human
P9159
Piperidine-4-sulfonic acid, ,
Especie
human
M-039
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human

Small Molecule - Allosteric Modulator

Número de producto
Descripción
Especie
Z-017
Zolpidem solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Z-004
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
1724350
Zaleplon, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Y0002139
Zolpidem for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard,
Especie
human
D5297
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Especie
human

Small Molecule - Antagonist

Número de producto
Descripción
Especie
N9890
Norfloxacin, analytical standard, ≥98% (TLC),
Especie
rat, human
17850
Ciprofloxacin, ≥98% (HPLC),
Especie
rat, human
O8757
Ofloxacin, fluoroquinolone antibiotic,
Especie
rat, human
E5126
Etiocholan-3α-ol-17-one, ,
Especie
human, rat
R109
Ro 15-4513, solid,
Especie
rat, human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
A2052
Anti-GABA antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
drosophila, rat, wide range
Aplicación
dot blot
immunohistochemistry
A0310
Monoclonal Anti-GABA antibody produced in mouse, clone GB-69, ascites fluid,
Reactividad de especies
wide range
Aplicación
ELISA
dot blot
immunofluorescence
immunohistochemistry
AB175
Anticuerpo anti-GABA, serum, Chemicon®,
Reactividad de especies
all, rat
Aplicación
ELISA
immunohistochemistry
05-474
Anti-GABA A Receptor β2/3 Antibody, clone 62-3G1, Upstate®, from mouse,
Reactividad de especies
bovine, human, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
ABN131
Anticuerpo anti-GABA, from rabbit, purified by affinity chromatography,
Reactividad de especies
all, rat
Aplicación
ELISA
immunohistochemistry

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
D175005
2,6-Dimethylphenol, 99%,
Especie
human
113263
1,3-Diisopropylbenzene, 96%,
Especie
human
129526
2-Isopropylphenol, 98%,
Especie
human
D174904
2,6-Dimethylphenol, ≥99.5%,
Especie
human
W324906
2,6-Dimethylphenol, ≥99%, FG,
Especie
human

Small Molecule - Ligand

Número de producto
Descripción
Especie
E7023
Alcohol etílico puro 200, Molecular Biology,
Especie
human
E6530
Etomidate, >98% (HPLC), powder,
Especie
human
F6300
Flumazenil, >99% (HPLC), solid,
Especie
rat, human
C4024
Carbamazepine, powder,
Especie
rat, human
B4388
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Especie
human

Small Molecule - Mixed Agonist/Antagonist

Número de producto
Descripción
Especie
P4557
Fenol solution, Equilibrated with 10 mM Tris HCl, pH 8.0, 1 mM EDTA, BioReagent, Molecular Biology,
Especie
human
P4682
Fenol solution, Saturated with 0.01 M citrate buffer, pH 4.3 ± 0.2, BioReagent, Molecular Biology,
Especie
human
W322318
Fenol, ≥99%,
Especie
human
P9346
Fenol solution, ≥89.0%,
Especie
human
33517
Fenol, puriss. p.a., ACS reagent, reag. Ph. Eur., 99.0-100.5%,
Especie
human

esiRNA

Número de producto
Descripción
Especie
EHU133951
MISSION® esiRNA, targeting human GABRA1,
Especie
human
EMU069331
MISSION® esiRNA, targeting mouse Gabra1,
Especie
mouse