Saltar al contenido
Merck

CTSB

cathepsin B

Sinónimos:
APPS, CPSB
Especie:
ID UniProtKB:
ID del gen:
  • Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13030) cathepsin B
  • Rat(64529) cathepsin B
  • domestic guinea pig(100714169) cathepsin B
  • naked mole-rat(101709008) cathepsin B
  • dog(486077) cathepsin B
  • Horse(100060963) cathepsin B
  • domestic cat(101084873) cathepsin B
  • cow(281105) cathepsin B
  • sheep(780470) cathepsin B
  • chicken(396329) cathepsin B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
Reactividad de especies
bovine, human, porcine
Aplicación
Anti-Cathepsin B Antibody, clone 6I5D7, Rabbit Monoclonal, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Monoclonal Anti- Cathepsin B antibody produced in mouse, clone CB59-4B11, purified from hybridoma cell culture,
Reactividad de especies
human, rat
Aplicación
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Z-Leu-Leu-Leu-al, ≥90% (HPLC),
Especie
human
Calpain Inhibitor I, ≥97% (TLC), powder,
Especie
human
MG-132(R), ≥95% (HPLC),
Especie
human
Diethylcyanamide, 99%,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
Cathepsin B from human liver, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
Especie
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Especie
human
Cathepsin B from bovine spleen, lyophilized powder, ≥10 units/mg protein,
Especie
cow
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Especie
human
Cathepsin B from human placenta, lyophilized powder, ≥5 units/mg protein,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Ctsb,
Especie
mouse
MISSION® esiRNA, targeting human CTSB,
Especie
human

Small Molecule - Substrate

Referencia del producto
Descripción
Especie
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride, ,
Especie
mouse, human, rat