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Merck

CHRNB1

cholinergic receptor, nicotinic, beta 1 (muscle)

Sinónimos:
ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
Especie:
ID UniProtKB:
ID del gen:
  • Human(1140) Summary: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(11443) cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
  • Rat(24261) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic cat(101097433) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Domestic Rabbit(100357163) cholinergic receptor, nicotinic, beta 1 (muscle)
  • sheep(101121614) cholinergic receptor, nicotinic, beta 1 (muscle)
  • naked mole-rat(101723288) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic guinea pig(100714100) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Zebrafish(100006941) cholinergic receptor, nicotinic, beta 1 (muscle)
  • dog(489473) cholinergic receptor, nicotinic, beta 1 (muscle)
  • cow(282179) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Horse(100072990) cholinergic receptor, nicotinic, beta 1 (muscle)

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Decamethonium bromide, Ion-Pair reagent, ≥99%,
Especie
human
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Especie
human, mouse, rat
(−)-Nicotina, ≥99% (GC), liquid,
Especie
human, mouse, rat
Decamethonium bromide, crystalline,
Especie
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Especie
human, rat

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Pancuronium bromide, ,
Especie
human
Cisatracurium besylate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Tubocurarine hydrochloride pentahydrate, ≥97%,
Especie
human
Atracurium besylate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
(+)-Tubocurarine chloride pentahydrate, ≥97.0% (TLC),
Especie
human

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Tetraethylammonium chloride, ≥98% (titration),
Especie
human
Hexamethonium bromide, ,
Especie
human
Hexamethonium chloride, solid (hygroscopic),
Especie
human
Kynurenic acid, ≥98%,
Especie
rat, human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CHRNB1,
Especie
human
MISSION® esiRNA, targeting mouse Chrnb1,
Especie
mouse