S8197
SMER28
>99% (HPLC), solid
Synonym(s):
6-Bromo-N-2-propenyl-4-quinazolinamine
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 mg | Please contact Customer Service for Availability | €172.00 €146.20 | |
| 25 mg | Please contact Customer Service for Availability | €772.00 |
About This Item
Empirical Formula (Hill Notation):
C11H10BrN3
CAS Number:
Molecular Weight:
264.12
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
>99% (HPLC)
Form:
solid
€146.20
List Price€172.00Save 15%Web-Only Promotion
Please contact Customer Service for Availability
Quality Segment
assay
>99% (HPLC)
form
solid
solubility
DMSO: >20 mg/mL, H2O: insoluble
storage temp.
2-8°C
SMILES string
Brc1ccc2ncnc(NCC=C)c2c1
InChI
1S/C11H10BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h2-4,6-7H,1,5H2,(H,13,14,15)
InChI key
BCPOLXUSCUFDGE-UHFFFAOYSA-N
Application
SMER28 may be used in mTOR-mediated signaling studies.
Biochem/physiol Actions
SMER28 is a small molecule modulator of mammalian autophagy.
SMER28 is a small molecule modulator of mammalian autophagy; enhances A53T alpha-synuclein clearance in PC-12 cells independent of rapamycin treatment; appears to act independent of the mTOR pathway, but combined treatment with saturating rapamycin concentration enhances the effect of either compound alone on A53T alpha-synuclein clearance; autophagy inducers may prove useful in the treatment of neurodegenerative and infectious diseases and cancer.
1 of 1
This Item | |||
|---|---|---|---|
| assay >99% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form solid | form powder | form solid | form powder |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: >20 mg/mL, H2O: insoluble | solubility DMSO: 2 mg/mL, clear | solubility DMSO: ~20 mg/mL, H2O: insoluble | solubility DMSO: 5 mg/mL, clear (warmed) |
Still not finding the right product?
Explore all of our products under SMER28
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S8197-5MG | 04061832982236 |
| S8197-25MG | 04061832982229 |