P4154
Polyinosinic acid potassium salt
Homopolymer
Synonym(s):
Poly(I) potassium salt
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 mg | Please contact Customer Service for Availability | €173.00 | |
| 25 mg | Please contact Customer Service for Availability | €339.00 | |
| 100 mg | Please contact Customer Service for Availability | €956.00 |
About This Item
Assay:
≥98% (TLC)
Biological source:
synthetic (organic)
Form:
lyophilized powder
Solubility:
water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow
Storage temp.:
−20°C
biological source
synthetic (organic)
Quality Level
assay
≥98% (TLC)
form
lyophilized powder
solubility
water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow
storage temp.
−20°C
Application
Polyinosinic acid (Poly(I)) is a homopolymer of inosine that may be used with polycytidylic acid (poly(C)) to form the double-stranded homopolymer (Poly(I) • Poly(C)). TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. (Poly(I) • Poly(C)) is a used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
Preparation Note
Prepared from IDP using polynucleotide phosphorylase.
1 of 1
This Item | |||
|---|---|---|---|
| biological source synthetic (organic) | biological source - | biological source - | biological source - |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form - |
| assay ≥98% (TLC) | assay ≥99% (less than 1% free nucleotides, TLC) | assay ≥98% (TLC) | assay ≥99% (TLC) |
| solubility water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow | solubility - | solubility water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless | solubility - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Gennady Dvoryanchikov et al.
Nature communications, 8(1), 760-760 (2017-10-04)
Taste buds are innervated by neurons whose cell bodies reside in cranial sensory ganglia. Studies on the functional properties and connectivity of these neurons are hindered by the lack of markers to define their molecular identities and classes. The mouse
Xingbo Wang et al.
Veterinary microbiology, 251, 108895-108895 (2020-10-31)
RNA binding ability and cellular distribution are important for nonstructural protein 1 (NS1) of influenza A virus to act as a viral regulatory factor to control virus life cycle. In this study, we identified that the N-terminal residues 19-21 of
Overlapping and distinct roles of GRK5 in TLR2-, and TLR3-induced inflammatory response in vivo.
Packiriswamy N, Parvataneni S, Parameswaran N.
Cellular Immunology, 107-111 (2011)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P4154-100MG | 04061834373612 |
| P4154-25MG | 04061833289921 |
| P4154-10MG | 04061834373629 |