C5938
Complement factor I from human plasma
>90% (SDS-PAGE)
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 0.1 mg | Please contact Customer Service for Availability | €575.00 |
About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Assay:
>90% (SDS-PAGE)
Biological source:
human plasma
Concentration:
0.95-1.20 mg/mL
Application
Complement factor I from human plasma has been used in a case study of glucose-starved Staphylococcus aureus. Complement factor I from human plasma has also been used to study the human complement cascade of proteolysis as a target of laser irradiation.
Biochem/physiol Actions
Protease which cleaves and inactivates C3b and C4b
Physical form
Supplied as a 1mg/ml solution in PBS, pH 7.2
Other Notes
View more information on the complement pathway at www.sigma-aldrich.com/enzymeexplorer
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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This Item | |||
|---|---|---|---|
| biological source human plasma | biological source human plasma | biological source human plasma | biological source human serum |
| assay >90% (SDS-PAGE) | assay ≥90% (SDS-PAGE) | assay ≥90% (SDS-PAGE) | assay ≥85% (SDS-PAGE) |
| technique(s) activity assay: suitable | technique(s) activity assay: suitable | technique(s) - | technique(s) activity assay: suitable |
| Gene Information human ... CFI(3426) | Gene Information human ... CFH(3075) | Gene Information human ... CFD(1675) | Gene Information human ... C7(730) |
| concentration 0.95-1.20 mg/mL | concentration 1 mg/mL in PBS, pH 7.2 | concentration 90-110 μg/mL in PBS, pH 7.2 | concentration 1 mg/mL in 10 mM sodium phosphate, 150 mM sodium chloride, pH 7.2 |
| form solution | form liquid | form liquid | form solution |
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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The study of the human complement cascade of proteolysis as a target of laser irradiation
Galebskaia, L., et al.
Biomeditsinskaia Khimiia, 55, 68-72 (2012)
Stephan Michalik et al.
Molecular & cellular proteomics : MCP, 11(9), 558-570 (2012-05-05)
The cellular amount of proteins not only depends on synthesis but also on degradation. Here, we expand the understanding of differential protein levels by complementing synthesis data with a proteome-wide, mass spectrometry-based stable isotope labeling with amino acids in cell
Sara C Nilsson et al.
Molecular immunology, 48(14), 1611-1620 (2011-05-03)
Factor I (FI) is a crucial inhibitor controlling all complement pathways due to its ability to degrade activated complement proteins C3b and C4b in the presence of cofactors such as factor H, C4b-binding protein, complement receptor 1 or CD46. Complete
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C5938-.1MG | 04061832700120 |