Stability information for A8185 in solution has not been reported. It would be advisable to make the solutions fresh.
If necessary, storage at -20°C in single-use aliquots for approximately one month can be attempted.
A8185
Ala-Gln
BioReagent, suitable for cell culture, suitable for insect cell culture
Synonym(s):
Alanyl-glutamine, Glutamine-S
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 g | Please contact Customer Service for Availability | €242.00 | |
| 100 g | Please contact Customer Service for Availability | €2,850.00 | |
| 1 kg | Please contact Customer Service for Availability | €15,940.00 |
About This Item
Empirical Formula (Hill Notation):
C8H15N3O4
CAS Number:
Molecular Weight:
217.22
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.75
product line
BioReagent
Quality Level
assay
≥98% (HPLC)
form
powder
technique(s)
cell culture | insect: suitable, cell culture | mammalian: suitable
color
white to off-white
storage temp.
room temp
SMILES string
NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O
InChI
1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1
InChI key
HJCMDXDYPOUFDY-WHFBIAKZSA-N
Application
Ala-Gln has been used:
- as a supplement in NeuralQ™ medium
- as a component in growth medium and incubation medium (IM) for retinal cell lines
- for experimental treatment of retinal cell lines respectively
Biochem/physiol Actions
Alanyl-glutamine (Ala-Gln) is a dipeptide that is used as a substitute for glutamine in mammalian cell culture media, because of the instability of glutamine in solution and the formation of ammonia as a breakdown product of glutamine in solution, which can have deleterious effects on cells in culture. Ala-Glu is stable to heat sterilization and is less ammonia genic than glutamine, which contributes to its advantages as a media component. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro.[1]
Analysis Note
This product is cell culture tested (0.5 mg/ml) and insect cell culture tested (0.2 mg/ml). It is appropriate for use in cell culture and insect cell culture applications at 2-10 mM.
Legal Information
NeuralQ is a trademark of GlobalStem
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This Item | |||
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| technique(s) cell culture | insect: suitable, cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) cell culture | insect: suitable, cell culture | mammalian: suitable |
| assay ≥98% (HPLC) | assay ≥99.5% (NT) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| product line BioReagent | product line BioUltra | product line - | product line BioReagent |
| storage temp. room temp | storage temp. - | storage temp. - | storage temp. - |
| color white to off-white | color white | color white to off-white | color white |
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
Product Information Sheet
Vinicius Fernandes Cruzat et al.
Cell biochemistry and function, 28(1), 24-30 (2009-11-04)
In this study, we investigated the effect of the supplementation with the dipeptide L-alanyl-L-glutamine (DIP) and a solution containing L-glutamine and L-alanine on plasma levels markers of muscle damage and levels of pro-inflammatory cytokines and glutamine metabolism in rats submitted
A high-throughput assay for mRNA silencing in primary cortical neurons in vitro with oligonucleotide therapeutics
Alterman JF, et al.
Bio-protocol, 7(16) (2017)
Vinicius Fernandes Cruzat et al.
Nutrition (Burbank, Los Angeles County, Calif.), 25(4), 428-435 (2008-12-06)
We investigated the effect of supplementation with the dipeptide L-alanyl-L-glutamine (DIP) and a solution containing L-glutamine and L-alanine, both in the free form, on the plasma and tissue concentrations of glutamine, glutamate, and glutathione (GSH) in rats subjected to long-duration
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A8185-1KG | 04061833391273 |
| A8185-100G | 04061833391266 |
| A8185-5G | 04061835568093 |
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What is the storage temperature for this product in water at 50mg/mL ?
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