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54880

3-Hydroxybenzylhydrazine dihydrochloride

≥98.0% (HPLC)

Synonym(s):

α-Hydrazino-m-cresol dihydrochloride, 3-(Hydrazinomethyl)phenol dihydrochloride, NSD-1015

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1 g
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€212.00
€180.20

About This Item

Linear Formula:
HOC6H4CH2NHNH2 · 2HCl
CAS Number:
81012-99-9
Molecular Weight:
211.09
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
24878937
EC Number:
279-659-3
Beilstein/REAXYS Number:
9282965
MDL number:
MFCD00044695
Assay:
≥98.0% (HPLC)
Form:
solid
Quality level:
100

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Quality Level

100

assay

≥98.0% (HPLC)

form

solid

mp

137-140 °C, 138-140 °C (lit.)

solubility

H2O: 50 mg/mL, slightly hazy, faintly yellow

SMILES string

Cl[H].Cl[H].NNCc1cccc(O)c1

InChI

1S/C7H10N2O.2ClH/c8-9-5-6-2-1-3-7(10)4-6;;/h1-4,9-10H,5,8H2;2*1H

InChI key

ONOJPUDFIOEGCX-UHFFFAOYSA-N

Biochem/physiol Actions

Inhibitor of L-aromatic amino acid decarboxylase; crosses blood brain barrier.
Inhibitor of L-aromatic amino acid decarboxylase; crosses blood brain barrier. Also inhibits GABA aminotransferase, as well as other pyridoxal-phosphate-requiring enzymes, by forming the 3-hydroxybenzylhydrazone of that cofactor.

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This Item
H139B4563SML0635
3-Hydroxybenzylhydrazine dihydrochloride ≥98.0% (HPLC)

Sigma-Aldrich

54880

3-Hydroxybenzylhydrazine dihydrochloride

HA-1077 dihydrochloride solid, ≥98% (HPLC)

Sigma-Aldrich

H139

HA-1077 dihydrochloride

Bisantrene dihydrochloride ≥98% (HPLC)

Sigma-Aldrich

B4563

Bisantrene dihydrochloride

AZD6765 dihydrochloride ≥97% (HPLC)

Sigma-Aldrich

SML0635

AZD6765 dihydrochloride

form

solid

form

solid

form

solid

form

powder

assay

≥98.0% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

H2O: 50 mg/mL, slightly hazy, faintly yellow

solubility

H2O: >10 mg/mL

solubility

deionized water: 8 mg/mL

solubility

H2O: 20 mg/mL, clear

mp

137-140 °C

mp

-

mp

-

mp

-

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBT7147
BCBG5065V
BCBB1136V
BCBB1136
1445429

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Articles

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V Mosienko et al.
Translational psychiatry, 2, e122-e122 (2012-07-27)
Serotonin is a major neurotransmitter in the central nervous system (CNS). Dysregulation of serotonin transmission in the CNS is reported to be related to different psychiatric disorders in humans including depression, impulsive aggression and anxiety disorders. The most frequently prescribed
Adrian M Russo et al.
Behavioural brain research, 359, 918-926 (2018-06-24)
Autism spectrum disorder (ASD) is a heterogeneous and highly heritable condition with multiple aetiologies. Although the biological mechanisms underlying ASD are not fully understood, evidence suggests that dysregulation of serotonergic systems play an important role in ASD psychopathology. Preclinical models
Gerard Honig et al.
PloS one, 4(8), e6797-e6797 (2009-08-28)
Serotonin (5-HT) is a neurotransmitter with important roles in the regulation of neurobehavioral processes, particularly those regulating affect in humans. Drugs that potentiate serotonergic neurotransmission by selectively inhibiting the reuptake of serotonin (SSRIs) are widely used for the treatment of
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Global Trade Item Number

SKUGTIN
54880-5G-F04061833021781
54880-1G-F04061832574912

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