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Leptophos

Name: Leptophos
Brand: SIAL
Price: 154 EUR

PESTANAL^®, analytical standard

Synonym(s):

O-(4-Bromo-2,5-dichlorophenyl) O-methyl phenylphosphonothioate

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Pack Size	SKU	Availability	Price
100 mg		Please contact Customer Service for Availability	€154.00

About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₀BrCl₂O₂PS

CAS Number:

21609-90-5

Molecular Weight:

412.07

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329754497

EC Number:

244-472-8

Beilstein/REAXYS Number:

2152663

MDL number:

MFCD00128037

€154.00

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Properties

grade

analytical standard

product line

PESTANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, NMR: suitable, gas chromatography (GC): suitable

mp

71-73 °C

suitability

passes test for identity (NMR)

application(s)

agriculture
environmental

format

neat

storage temp.

2-8°C

SMILES string

COP(=S)(Oc1cc(Cl)c(Br)cc1Cl)c2ccccc2

InChI

1S/C13H10BrCl2O2PS/c1-17-19(20,9-5-3-2-4-6-9)18-13-8-11(15)10(14)7-12(13)16/h2-8H,1H3

InChI key

CVRALZAYCYJELZ-UHFFFAOYSA-N

Description

General description

Leptophos, an organophosphorus insecticide found to be persistent in the environment, shows neurotoxic effects in humans. Its mode of action for pest control involves the inhibition of acetylcholinesterase enzyme activity.

Application

Leptophos may be used as an analytical reference standard for the quantification of the analyte in vegetables using solid phase micro-extraction coupled with gas chromatography-flame photometric detector (SPME-GC-FPD).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item	CRM43602	36126	46279
Supelco 33366 Leptophos	Supelco CRM43602 Leptophos	Supelco 36126 Chlorthiophos	Supelco 46279 Cyanophos
format neat	format -	format neat	format neat
technique(s) HPLC: suitable, gas chromatography (GC): suitable, NMR: suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable
grade analytical standard	grade certified reference material, TraceCERT^®	grade analytical standard	grade analytical standard
product line PESTANAL^®	product line TraceCERT^®	product line PESTANAL^®	product line PESTANAL^®
mp 71-73 °C	mp -	mp -	mp -
suitability passes test for identity (NMR)	suitability -	suitability -	suitability -

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pictograms

GHS06,GHS08,GHS09

signalword

Danger

hcodes

H300,H311,H370,H410

pcodes

P260 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P312

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

flash_point_f

>212.0 °F

flash_point_c

> 100 °C

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Determination of organophosphorus pesticide residues in vegetables using solid phase micro-extraction coupled with gas chromatography-flame photometric detector.

Sapahin AH, et al.

Arabian Journal of Chemistry, 23(1), 636-641 (2014)

Effects of various post-treatment by phenylmethylsulfonyl fluoride on delayed neurotoxicity induced by leptophos.

F Y Piao et al.

The Journal of toxicological sciences, 20(5), 609-617 (1995-11-01)

Delayed neurotoxicity induced by leptophos, an organophosphorus insecticide, was intensified in hens when phenylmethylsulfonyl fluoride (PMSF) at dose of 30, 60, and 120 mg/kg body weight was administered at different time intervals (24 hr, 3 days, and 5 days) for

Effects of multiple dosing of fenthion, fenitrothion, and desbromoleptophos in young chicks.

M Farage-Elawar et al.

Journal of toxicology and environmental health, 23(2), 217-228 (1988-01-01)

The effects of multiple doses of desbromoleptophos, fenitrothion, and pure fenthion on brain acetylcholinesterase (AChE), brain neurotoxic esterase (NTE), and walking were investigated in immature chicks, below the age of sensitivity to organophosphorus ester-induced delayed neurotoxicity (OPIDN). Ten milligrams per