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20-107

Peroxynitrite

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Size/SKUAvailabilityPrice
5 mL
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€373.00

About This Item

UNSPSC Code:
41116012
NACRES:
NA.41
eCl@ss:
32160405
Form:
liquid

€373.00

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form

liquid

Quality Segment

100

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

shipped in

dry ice

General description

Peroxynitrite (ONOO−) is a powerful oxidant formed by the collision of nitric oxide and superoxide.[1]

Application

Peroxynitrite has been used to induce pericyte contraction in mouse brains.[1] It has also been used for the preparation of positive control nitrated protein standards in immunohistochemical studies.[2]

Biochem/physiol Actions

Peroxynitrite (ONOO−) exhibits bactericidal activity.[3] It promotes cell death and contributes to the signal-transduction process, mitochondrial function, and apoptotic pathway. The formation of peroxynitrite has been associated with the development of various diseases including vascular diseases, ischemia-reperfusion injury, circulatory shock, inflammation, pain, and neurodegeneration.[1]

Physical form

0.3M NaOH

Analysis Note

Routinely evaluated by treating non-stimulated A431 cells.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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1 of 1

This Item
516620SCT035N0409
Peroxynitrite

Sigma-Aldrich

20-107

Peroxynitrite

Peroxynitrite Synthesized from isoamyl nitrite and hydrogen peroxide.

Sigma-Aldrich

516620

Peroxynitrite

BioTracker 515 Green ONOO- Dye Live cell imaging dye for peroxynitrite (ONOO-) used to detect reactive oxygen species (ROS) generated from the interaction of nitric oxide (NO) and superoxide (O).

Sigma-Aldrich

SCT035

BioTracker 515 Green ONOO- Dye

Anti-Nitrotyrosine antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

N0409

Anti-Nitrotyrosine antibody produced in rabbit

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

200

form

liquid

form

liquid

form

-

form

buffered aqueous solution

manufacturer/tradename

Upstate®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

technique(s)

western blot: suitable

technique(s)

-

technique(s)

cell based assay: suitable

technique(s)

immunohistochemistry (frozen sections): 1:1000 using methacarn-fixed, frozen sections of human Alzheimer′s Disease brain, indirect ELISA: 1:1,000 using nitrated-BSA, indirect immunofluorescence: 1:1,000 using A549 cells metabolically labeled with 3-nitrotyrosine, microarray: suitable, western blot: 1:1,000 using nitrated-BSA

shipped in

dry ice

shipped in

wet ice

shipped in

ambient

shipped in

dry ice

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pictograms

Corrosion
GHS05

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids

Certificates of Analysis (COA)

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