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Anti-FADD Antibody, clone 1F7

Name: Anti-FADD Antibody, clone 1F7
Brand: MM
Price: 583 EUR

clone 1F7, Upstate^®, from mouse

Synonym(s):

Anti-GIG3, Anti-IMD90, Anti-MORT1

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Pack Size	SKU	Availability	Price
100 μg		Please contact Customer Service for Availability	€583.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

1F7, monoclonal

Application:

Citations:

€583.00

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Properties

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

1F7, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Upstate^®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

NM_003824

UniProt accession no.

Q13158

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... FADD(8772)
mouse ... Fadd(14082)

Description

General description

28kDa

Immunogen

GST-tagged full-length fusion protein corresponding to human FADD

Application

Anti-FADD Antibody, clone 1F7 detects level of FADD & has been published & validated for use in WB.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Biochem/physiol Actions

FADD

Physical form

Format: Purified

PBS, pH 7.2 and 50% glycerol

Protein A chromatography

Preparation Note

2 years at -20°C

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.

routinely evaluated by immunoblot on RIPA lysates from Jurkat cells

Other Notes

Replaces: 04-1113

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	HPA038568	S0697	SAB4301377
Sigma-Aldrich 05-486 Anti-FADD Antibody, clone 1F7	Sigma-Aldrich HPA038568 Anti-MADD antibody produced in rabbit	Sigma-Aldrich S0697 Anti-Sortilin antibody produced in rabbit	Sigma-Aldrich SAB4301377 Anti-phospho-FADD (pSer¹⁹¹) antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate -
clone 1F7, monoclonal	clone polyclonal	clone polyclonal	clone polyclonal
biological source mouse	biological source rabbit	biological source rabbit	biological source rabbit
species reactivity mouse, human	species reactivity human	species reactivity mouse, rat, human	species reactivity mouse, human
antibody form purified antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
technique(s) western blot: suitable	technique(s) immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:1000-1:2500	technique(s) immunohistochemistry: suitable, western blot: 1:200 using rat brain lysates	technique(s) immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000 (Cell Lysate)

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation.

Hayley I Muendlein et al.

Science (New York, N.Y.), 367(6484), 1379-1384 (2020-03-21)

Cell death and inflammation are interdependent host responses to infection. During pyroptotic cell death, interleukin-1β (IL-1β) release occurs through caspase-1 and caspase-11-mediated gasdermin D pore formation. In vivo, responses to lipopolysaccharide (LPS) result in IL-1β secretion. In vitro, however, murine

Suppression of TNF receptor-1 signaling in an in vitro model of epileptic tolerance.

Thompson, SJ; Ashley, MD; Stohr, S; Schindler, C; Li, M; McCarthy-Culpepper, KA; Pearson et al.

International Journal of Physiology, Pathophysiology and Pharmacology null

Death domain mutagenesis of KILLER/DR5 reveals residues critical for apoptotic signaling

McDonald, E. R., 3rd, et al

The Journal of Biological Chemistry, 276, 14939-14945 (2001)

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Global Trade Item Number

SKU	GTIN
05-486	04053252273124

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