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798088
Fluorescent nanodiamond
Nitrogen vacancy ~3 ppm NV centers, 120 nm avg. part. size, 1 mg/mL in deionized water
Synonym(s):
Diamond nanopowder, Nanodiamonds
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5 ML
€414.00
About This Item
Linear Formula:
C
UNSPSC Code:
12352302
NACRES:
NA.23
Recommended Products
form
suspension
Quality Level
composition
Nitrogen vacancy, ~3 ppm NV centers
concentration
1 mg/mL in deionized water
avg. part. size
120 nm
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General description
Fluorescent nanodiamonds (FNDs) can be prepared by subjecting synthetic diamond nanocrystallites to helium ions.[1] FND is biocompatible and its surface can be easily functionalized. It is a very useful tool in bioimaging mainly because the photons emitted from the defect centers of FND upon laser excitation can easily penetrate the tissue. The emission from FNDs is extremely stable.[1] The average size of the FNDs is 120 nm.
In fluorescent nanodiamonds, the nitrogen vacancy centers in the diamond lattice provide the fluorescence; unlike the quantum dots or organic dyes, the color centers in these don′t photobleach or photoblink. These outstanding properties of fluorescent nanodiamonds along with their biocompatibility, large surface area etc. make them promising bioimaging probes.
Product can be functionalized with carboxylic acid, hydroxyl, ketones, ethers, and/or hydrogen.
Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Articles
Fluorescent Nanodiamond Particles (FNDs)- Find properties and applications of nanodiamond particles.
Fluorescent Nanodiamonds and biofunctionalization strategies are detailed for imaging and bioconjugation applications.
Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.
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I would like to see the fluorescence response of 798088
1 answer -
1. Is your inflorescence nanodiamond dyed?
2. What are the excitation and emission wavelengths for them? are their quantum yield and brightness information available?
3. What is the function of the PEG functionalization here? Does it reduce surface tension? Does the functional group affect the fluorescent intensity?
4. Has it been used for some fluorescent tracing experiments?1 answer-
1 The fluorescence originates from the nanodiamonds centers, such as nitrogen-vacancy (NV), NVN, or N3, and not from any fluorescent groups. Therefore, it is not dyed.
2 The excitation/emission wavelengths are consistent for these products and are based on the nanodiamonds center. The catalog part numbers, center type, excitation peak, emission peak, and brightness information are as follows:
900173, NVN, 480 nm, 520 nm (green), ~90x vs FITC
All other products, NV, 570 nm, 680 nm (red), ~70x brighter vs Atto 647 Two important notes provided were:
Green fluorescence is brighter than red.
Longer wavelengths, such as red light, have better penetrability.
3 PEG functionalization historically reduces non-specific binding and aggregation in buffered media. Carboxylated particles are commonly used for sensing and imaging applications, or to conduct further syntheses in the lab. However, in biological media/buffer (e.g., PBS), they are prone to aggregation, and surface coatings help to reduce this. Moreover, other functionalizations, such as biotin or antibodies, allow for selective targeting.
4 Threr is information available that it has been used in fluorescent imaging experiments.Helpful?
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