1304038

Identificación de la heparina sódica

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Heparina sodium
• Número CAS: 9041-08-1
• MDL number: MFCD00081689
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: pharmaceutical primary standard
• agency: USP
• API family: heparin
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: [Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O
• InChI: 1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-
• InChI key: JRTRSJGZMRQDHI-UHFFFAOYSA-N

Descripción

General description

La heparina sódica es la sal de sodio de los glucosaminoglucanos sulfatados. Es una mezcla de moléculas heterogéneas de pesos moleculares variables con una combinación de actividades contra diferentes factores de la cascada de la coagulación sanguínea. Está presente en los tejidos de los mamíferos y generalmente se obtiene de la mucosa intestinal u otros tejidos adecuados de los mamíferos domésticos utilizados para la alimentación humana. El patrón de referencia USP de identificación de la heparina sódica se proporciona según lo publicado y especificado por la farmacopea emisora. Toda la información proporcionada en apoyo de este producto, incluidas las SDS y cualquier folleto de información sobre el producto se ha elaborado y publicado bajo la autoridad de la farmacopea emisora. Si desea más información y soporte, diríjase a la página Web de la Farmacopea emisora.

Heparin sodium identification is a reference standard used for structural and compositional verification of UFH. It enables spectroscopic and chromatographic analysis to ensure the identity of heparin in pharmaceutical products.

The USP biologics carbohydrates category includes a variety of carbohydrate-based substances that are essential in the development and manufacturing of therapeutic products. These carbohydrates play crucial roles in biological processes and are often utilized as excipients, stabilizers, or active ingredients in pharmaceuticals. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of carbohydrate therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

El patrón de referencia USP para la identificación de heparina sódica se utiliza para preparar la disolución patrón y la disolución de idoneidad del sistema para la identificación y el análisis de la heparina sódica utilizando métodos específicos como los descritos en las monografías de la Farmacopea de los Estados Unidos (USP). Encontrará más información en el capítulo, Heparin Sodium, USP43-NF38 – 2195 de la USP.

Other Notes

Heparin Sodium is the sodium salt of sulfated glycosaminoglycans. It is a mixture of heterogeneous molecules varying in molecular weights with a combination of activities against different factors of the blood clotting cascade. It is present in mammalian tissues and is usually obtained from the intestinal mucosa or other suitable tissues of domestic mammals used for food by humans. Heparin sodium identification USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

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Este producto es parte del programa USP Biologics.

Heparin Sodium is the sodium salt of sulfated glycosaminoglycans. It is a mixture of heterogeneous molecules varying in molecular weights with a combination of activities against different factors of the blood clotting cascade. It is present in mammalian

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable