1304107

Calibrador de peso molecular de heparina sódica

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Heparina sodium salt solution
• Número CAS: 9041-08-1
• UNSPSC Code: 41116107
• NACRES: NA.24
• MDL number: MFCD00081689

Propiedades

• grade: pharmaceutical primary standard
• agency: USP
• API family: heparin
• form: powder
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: [Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O
• InChI: 1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-
• InChI key: JRTRSJGZMRQDHI-UHFFFAOYSA-N

Descripción

General description

La heparina sódica es una mezcla de glucosaminoglucanos sulfatados en forma de sal de sodio. Se compone de moléculas heterogéneas con diferentes pesos moleculares, exhibiendo colectivamente múltiples actividades que afectan a diversos factores involucrados en el proceso de coagulación de la sangre. Esta sustancia aparece de forma natural en los tejidos de los mamíferos y suele proceder de fuentes tales como la mucosa intestinal u otros tejidos aplicables obtenidos de mamíferos domésticos comúnmente consumidos como alimento por los seres humanos. El patrón de referencia USP de calibración del peso molecular de la heparina sódica se proporciona según lo publicado y especificado por la farmacopea emisora. Toda la información proporcionada en apoyo de este producto, incluidas las MSDS y cualquier folleto de información sobre el producto se ha elaborado y publicado bajo la autoridad de la farmacopea emisora. Si desea más información y soporte, diríjase a la página Web de la Farmacopea emisora.

This molecular weight calibrant standard is essential for the determination of heparin′s molecular weight distribution via size exclusion chromatography. Accurate molecular profiling ensures the safety and efficacy of heparin products and supports regulatory submission data.

The USP biologics carbohydrates category includes a variety of carbohydrate-based substances that are essential in the development and manufacturing of therapeutic products. These carbohydrates play crucial roles in biological processes and are often utilized as excipients, stabilizers, or active ingredients in pharmaceuticals. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of carbohydrate therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Patrón de referencia USP de calibración del peso molecular de la heparina sódica, indicado para ser utilizado en pruebas y ensayos de calidad específicos según lo especificado en la farmacopea USP. También, para ser utilizado con monografías de la USP tales como la heparina sódica

Other Notes

Heparin Sodium is a mixture of sulfated glycosaminoglycans in the form of sodium salt. It is composed of heterogeneous molecules with different molecular weights, collectively exhibiting multiple activities that affect various factors involved in the blood clotting process. This substance naturally occurs in mammalian tissues and is typically derived from sources such as the intestinal mucosa or other applicable tissues obtained from domestic mammals commonly consumed as food by humans. Heparin Sodium Molecular Weight Calibrant USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

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Este producto es parte del programa USP Biologics.

Heparin Sodium is a mixture of sulfated glycosaminoglycans in the form of sodium salt. It is composed of heterogeneous molecules with different molecular weights, collectively exhibiting multiple activities that affect various factors involved in the bloo

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable