Saltar al contenido
Merck
Todas las fotos(1)

Documentos

S9317

Sigma-Aldrich

PAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt

≥97% (HPLC)

Sinónimos:

PAR2-AP, SLIGRL−NH2, Ser-Leu-Ile-Gly-Arg-Leu-amide trifluoroacetate salt

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C29H56O7N10 · C2HF3O2
Peso molecular:
770.84
MDL number:
MFCD03093421
UNSPSC Code:
51111800
PubChem Substance ID:
329824620
NACRES:
NA.32

Quality Level

200

assay

≥97% (HPLC)

form

solid

storage temp.

−20°C

SMILES string

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O

InChI

1S/C29H56N10O7/c1-7-17(6)23(39-27(45)21(12-16(4)5)38-25(43)18(30)14-40)28(46)35-13-22(41)36-19(9-8-10-34-29(32)33)26(44)37-20(24(31)42)11-15(2)3/h15-21,23,40H,7-14,30H2,1-6H3,(H2,31,42)(H,35,46)(H,36,41)(H,37,44)(H,38,43)(H,39,45)(H4,32,33,34)/t17-,18-,19-,20-,21-,23-/m0/s1

InChI key

SGPMJRPYYIJZPC-JYAZKYGWSA-N

Amino Acid Sequence

Ser-Leu-Ile-Gly-Arg-Leu-NH2

Application

PAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt has been used as a proteinase-activated receptor 2 (PAR-2) agonist to induce the expression of Hh and Hippo genes in Hek293A cells.

Biochem/physiol Actions

Selective proteinase-activated receptor 2 (PAR2) peptide agonist.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

The Yes-associated protein controls the cell density regulation of Hedgehog signaling
M. Tariki
Oncogenesis (2014)
Hyun Su Ha et al.
Archives of pharmacal research, 40(12), 1443-1454 (2017-11-04)
Protease-activated receptors (PARs) are a family of G protein-coupled receptors with a unique activation mechanism involving proteolytic cleavage of the extracellular N-terminal domain of the receptor. PAR2 has a contractile effect on esophageal smooth muscle. We investigate the signaling pathways
Chengcheng Huang et al.
Frontiers in molecular neuroscience, 10, 205-205 (2017-07-14)
Itch, a sensation eliciting a desire to scratch, is distinct from but not completely independent of pain. Inspiring achievements have been made in the characterization of itch-related receptors and neurotransmitters, but the molecular mechanisms controlling the development of pruriceptors remain
William G Darby et al.
Pharmacological research, 133, 152-159 (2018-05-23)
The aim of this study was to better understand the role of TRPV4 in the regulation of blood vessel dilatation by blood flow and activation of GPCRs. Using pressure myography, the dilator responses to the TRPV4 agonist GSK1016790A and to
Chihiro Hirai et al.
Reproductive sciences (Thousand Oaks, Calif.), 23(11), 1542-1550 (2016-05-04)
The production of soluble fms-like tyrosine kinase 1 (sFLT1) by exogenous chymotrypsin in trophoblast cells through protease-activated receptor (PAR) 2 was investigated to identify the role of a chymotrypsin-like serine protease in preeclampsia (PE) pathogenesis. We evaluated the expression of
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico