P8390

Picrotoxinin

• Fórmula empírica (notación de Hill): C₁₅H₁₆O₆
• Número de CAS: 17617-45-7
• Peso molecular: 292.28
• Número MDL: MFCD00078765
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 24898746
• NACRES: NA.77

Propiedades

• Formulario: powder
• cadena SMILES: [H][C@@]12OC(=O)[C@]([H])([C@@H]1C(C)=C)[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@@]2([H])[C@]35C
• InChI: 1S/C15H16O6/c1-5(2)7-8-11(16)19-9(7)10-13(3)14(8,18)4-6-15(13,21-6)12(17)20-10/h6-10,18H,1,4H2,2-3H3/t6-,7+,8+,9-,10-,13-,14-,15+/m1/s1
• Clave InChI: PIMZUZSSNYHVCU-KBLUICEQSA-N

Descripción

Descripción general

Picrotoxinin is a component of picrotoxin and can be derived from plants. It is a non-nitrogenous compound.

Aplicación

Picrotoxinin has been used as an agonist of taste 2 receptor member 14 (TAS2R14) to perform an array-based bitter receptor screening assay and to study the effect of calcium buffering and calcium sensor type on its sensitivity.

Acciones bioquímicas o fisiológicas

GABA_A receptor antagonist; binds to the GABA receptor-linked Cl⁻ channel.

Picrotoxinin acts as a potent convulsant.

Características y beneficios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glycine Receptor page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Otras notas

Active component of picrotoxin

Información de seguridad

• Pictogramas: GHS06
• Palabra de señalización: Danger
• Frases de peligro: H300
• Consejos de prudencia: P301 + P310 + P330
• Clasificaciones de peligro: Acute Tox. 2 Oral
• Código de clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges