O5500
Osmium tetroxide
Sealed ampule.
Sinónimos:
Osmium(VIII)-oxide, ‘Osmic acid’
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About This Item
Fórmula lineal:
OsO4
Número de CAS:
Peso molecular:
254.23
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de la sustancia en PubChem:
NACRES:
NA.47
Formulario:
powder
Productos recomendados
densidad de vapor
8.8 (vs air)
Nivel de calidad
presión de vapor
7 mmHg ( 20 °C)
Formulario
powder
idoneidad de la reacción
reagent type: oxidant
bp
130 °C (lit.)
mp
39.5-41 °C (lit.)
cadena SMILES
O=[Os](=O)(=O)=O
InChI
1S/4O.Os
Clave InChI
VUVGYHUDAICLFK-UHFFFAOYSA-N
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Categorías relacionadas
Descripción general
Osmium tetroxide (OsO4) is a heavy tetrahedral, symmetrical molecule composed of osmium, a third-row transition metal. Osmium tetroxide is both a dye, and a non-coagulant fixative agent in electron microscopy primarily used for the examination of biological tissue components in the histopathology laboratory. Specimens are postfixed with osmium testroxide to ensure preservation of the lipids.
Aplicación
Osmium tetroxide has been used as a fixative reagent for Brevibacterium mcbrellneri, and curcumin treated human lung cancer cell lines′ observation with a scanning electron microscope. It is also suitable as a fixative for ultrastructural analysis of Toxoplasma gondii′s skeletal muscle cells.
Acciones bioquímicas o fisiológicas
Osmium tetroxide chemically combines with lipids making them insoluble; only 7% of the lipids can be extracted after the fixation. Therefore, the cell membranes comprising phospholipids become black and electron-dense after fixation in osmium tetroxide. It is also used to fix small amount of fat maintained in sections during paraffin processing.
Otras notas
Due to the hazardous nature of osmium tetroxide, it is recommended to use an ampule opener when using this chemical.
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Referencia del producto
Descripción
Precios
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B
Código de clase de almacenamiento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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