H6166
Interferon α 2B human
HumanKine®, ≥95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture
Sinónimos:
IFN α 2B, IFN Alfa 2b, INF α 2B, INF Alfa 2b, Interferon Alfa 2b
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About This Item
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Nombre del producto
Interferon α 2B human, IFN-α 2B, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
origen biológico
human
Nivel de calidad
recombinante
expressed in HEK 293 cells
Ensayo
≥95% (SDS-PAGE)
Formulario
lyophilized powder
potencia
≤0.12 ng/mL EC50
calidad
endotoxin tested
mol peso
dimer 16 kDa (glycosylated)
envase
poly bottle of 10 μg (in poly bottle)
fabricante / nombre comercial
HumanZyme
técnicas
cell culture | mammalian: suitable
impurezas
≤1EU/mg
Nº de acceso UniProt
temp. de almacenamiento
−20°C
Información sobre el gen
human ... IFNA2(3440)
Descripción general
The interferon α 2 (IFN-α2) exists in three forms 2a, 2b and 2c. It consists of 165 amino acids and five α helices. IFN-α2B is found structurally stable at pH 7. The recombinant IFN-α is nonglycosylated compared to the natural human IFN-α.
Acciones bioquímicas o fisiológicas
Interferon α 2B (IFN-α 2B) belongs to the type I interferon protein family. It is produced by many cell types in response to viral infection. IFN-α 2B has antiproliferative and antitumor activities, as well as induction of apoptosis and the inflammatory response. It enhances the expression of MHC proteins by increasing the presentation of antigen peptides and activates cytotoxic T-cells.
Forma física
Lyophilized from a 0.2 μm filtered solution of 1x PBS.
Nota de preparación
HumanKine IFN-α 2B is a glycosylated monomer expressed in HEK 293 cells with an apparent molecular mass of 16 kDa. Production in human 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
Nota de análisis
The specific activity was determined by the dose-dependent proliferation of WISH (heteroploid human amnion cell line) in presence of VSV ( vesicular stomatitis virus).
Información legal
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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