D4788

2′-Deoxyadenosine 5′-triphosphate sodium salt solution

100 mM, pH 7

• Sinónimos: dATP
• Número CE: 217-662-3
• Código UNSPSC: 41106305
• eCl@ss: 32160414
• ID de la sustancia en PubChem: 24893898
• NACRES: NA.52

Propiedades

• Ensayo: ≥99%
• Formulario: liquid
• concentración: 100 mM
• color: colorless
• pH: 7
• actividad extraña: DNase, RNase, none detected
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [Na+].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O3
• InChI: 1S/C10H16N5O12P3.Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19;/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);/q;+1/p-1/t5-,6+,7+;/m0./s1
• Clave InChI: YJWCICGGRLOGEH-VWZUFWLJSA-M

Descripción

Descripción general

2′-Deoxyadenosine 5′-triphosphate (dATP) is made up of a nucleobase attached to deoxyribose and a 5′-hydroxyl on the sugar bound to a chain of three phosphate residues. dATP is used by cells for synthesis of DNA by DNA polymerases.

Aplicación

2′-Deoxyadenosine 5′-triphosphate sodium salt solution has been used in the detection of apoptotic cells by the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) technique. It has also been used to induce oligomerization of apoptotic protease activating factor-1 (Apaf-1) to form a large heptameric complex referred to as the apoptosome or Apaf-1 procaspase-9 apoptosome complex and to study its functions as a proteolytic-based molecular timer.

2′-Deoxyadenosine 5′-triphosphate sodium salt solution is used in DNA sysnthesis reactions such as PCR, DNA sequencing and molecular cloning techniques.

Componentes

T4 DNA Ligaes is supplied in a solution containing 20 mM Tris-HCl(ph 7.5), 50mM KCl, 1mM DTT, and 50% (v/v) glycerol

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable