C9523

Sodium cholesteryl sulfate

• Sinónimos: 5-Cholesten-3β-ol sulfate sodium salt, Cholesterol 3-sulfate sodium salt, Cholesteryl sodium sulfate, Cholesteryl sulfate sodium salt
• Fórmula empírica (notación de Hill): C₂₇H₄₅NaO₄S
• Número de CAS: 2864-50-8
• Peso molecular: 488.70
• Beilstein: 3899884
• Número MDL: MFCD00079091
• Código UNSPSC: 41141804
• eCl@ss: 39023139
• ID de la sustancia en PubChem: 24893166
• NACRES: NA.77

Propiedades

• origen biológico: synthetic
• descripción: anionic
• Ensayo: ≥98% (TLC)
• Formulario: powder
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• cadena SMILES: [H][C@@]([C@H](C)CCCC(C)C)([C@@]1(C)CC[C@@]23[H])CC[C@]1([C@](CC=C4C[C@H](CC[C@]34C)OS([O-])(=O)=O)2[H])[H].[Na+]
• InChI: 1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1
• Clave InChI: LMPVQXVJTZWENW-KPNWGBFJSA-M

Descripción

Aplicación

Sodium cholesteryl sulfate was used as the source of cholesterol in the preparation of Edgar′s growth medium used for embryology experiments. It was used as a standard for the separation of human stratum corneum lipids by thin layer chromatography.

Acciones bioquímicas o fisiológicas

Cholesteryl sulfate is a natural constituent of human spermatozoa and has major role in the maturation of sperms. It could also be involved in the capacitation of sperms and enables ovum penetration. Low concentrations of cholesteryl sulfate inhibits acrosin, the proteinase present in sperm acrosome that facilitates ovum penetration.

Nota de preparación

Sodium cholesteryl sulfate yields clear, colorless solution in chloroform-methanol (1:1) mixture at 10 mg/ml.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)