251R-1

Factor XIIIa (EP3372) Rabbit Monoclonal Primary Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: culture supernatant
• tipo de anticuerpo: primary antibodies
• clon: EP3372, monoclonal
• descripción: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formulario: buffered aqueous solution
• reactividad de especies: human
• envase: vial of 0.1 mL concentrate (251R-14); vial of 0.5 mL concentrate (251R-15); bottle of 1.0 mL predilute (251R-17); vial of 1.0 mL concentrate (251R-16); bottle of 7.0 mL predilute (251R-18)
• fabricante / nombre comercial: Cell Marque^®
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• isotipo: IgG
• control: dermatofibroma
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: cytoplasmic
• Información sobre el gen: human ... F13A1(2162)

Descripción

Descripción general

Factor XIIIa is a plasma transglutaminase that is part of the blood coagulation cascade and plays a critical role in stabilizing fibrin networks at the site of an injury to produce a clot. Factor XIIIa is expressed in platelets, megakaryocytes, fibroblast-like cells in the placenta, uterus, and prostate, monocytes and macrophages, and dermal dendritic cells. Anti-Factor XIIIa immunohistochemistry is used to identify fibrohistiocytic neoplasms such as dermatofibroma.
Factor XIIIa is a blood proenzyme that has been identified in platelets, megakaryocyte, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present in monocytes and macrophages and dermal dendritic cells. Anti- Factor XIIIa has been found to be useful in differentiating between dermatofibroma (90% (+)), dermatofibrosarcoma protuberans (25%(+)) and desmoplastic malignant melanoma (0%(+)). Factor XIIIa positivity is also seen in capillary hemagioblastoma (100%(+)), hemangioendothelioma (100%(+)), hemangiopericytoma (100%(+)), xanthogranuloma (100%(+)), xanthoma (100(+)), hepatocellular carcinoma (93%(+)), glomus tumor (80%(+)), and meningioma (80 % (+)).

Calidad

IVD

IVD

IVD

RUO

Ligadura / enlace

Factor XIIIa Positive Control Slides , Product No. 251S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

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Otras notas

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Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany