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M6035

Sigma-Aldrich

4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt

powder

Sinónimos:

Sulfo-SMCC

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About This Item

Fórmula empírica (notación de Hill):
C16H17N2NaO9S
Número de CAS:
92921-24-9
Peso molecular:
436.37
Número MDL:
MFCD00054978
Código UNSPSC:
12171500
ID de la sustancia en PubChem:
24897071
NACRES:
NA.47

Formulario

powder

Nivel de calidad

300

idoneidad de la reacción

reagent type: linker

técnicas

titration: suitable

color

white to light brown

solubilidad

H2O: 2.5 mg/mL
DMF: soluble

aplicaciones

diagnostic assay manufacturing
hematology
histology

temp. de almacenamiento

2-8°C

cadena SMILES

O=C(N1CC2CCC(C(ON3C(CC(S(=O)(O[Na])=O)C3=O)=O)=O)CC2)C=CC1=O

InChI

1S/C16H18N2O9S.Na/c19-12-5-6-13(20)17(12)8-9-1-3-10(4-2-9)16(23)27-18-14(21)7-11(15(18)22)28(24,25)26;/h5-6,9-11H,1-4,7-8H2,(H,24,25,26);/q;+1/p-1

Clave InChI

VUFNRPJNRFOTGK-UHFFFAOYSA-M

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Descripción general

4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt (sulfoSMCC) is a heterobifunctional protein/peptide cross-linker and a suitable cross-coupling reagent.

Acciones bioquímicas o fisiológicas

4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt is known to introduce a well-defined number of maleimide groups into the protein which confers them a long shelf-life at low temperatures and can be further labeled with Fluorine-18[18F].

Calidad

May contain dimethylformamide.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
WXBF3455V
WXBF3025V
WXBF4082V
WXBF0912V
WXBF2308V

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Glenn A O Cremers et al.
Bioconjugate chemistry, 30(9), 2384-2392 (2019-08-24)
The combination of the specificity of antibodies and the programmability of DNA nanotechnology has provided the scientific community with a powerful tool to label and unambiguously distinguish a large number of subcellular targets using fluorescence-based read-out methods. Whereas primary antibodies
Silica-coated CdTe quantum dots functionalized with thiols for bioconjugation to IgG proteins.
Wolcott A, et. al.
The Journal of Physical Chemistry B, 110, 5779-5779 (2006)
Ivana Giangrieco et al.
Molecular immunology, 112, 347-357 (2019-06-30)
Peach and apricot can cause allergic reactions with symptoms ranging from mild to very severe, including anaphylaxis. Sometimes subjects allergic to fruits of the Prunus genus have been reported to be also allergic to rubber latex products. The objective of
Xiajun Hu et al.
Scientific reports, 7(1), 12580-12580 (2017-10-05)
We developed a virus-like particle (VLP)-based therapeutic vaccine against angiotensin II receptor type 1, ATR-AP205-001, which could significantly reduce the blood pressure and protect target organs of hypertensive animals. In this study, we focused on the immunological effect and safety
Renshaw S
Immunohistochemistry and Immunocytochemistry: Essential Methods (2017)
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