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72210

Sigma-Aldrich

Neutral Red

for microscopy (Bact., Bot., Fl., Hist., Vit.), indicator (pH 6.8-8.0)

Sinónimos:

3-Amino-7-dimethylamino-2-methylphenazine hydrochloride, Basic Red 5, Toluylene red

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About This Item

Fórmula empírica (notación de Hill):
C15H17ClN4
Número de CAS:
553-24-2
Peso molecular:
288.78
Colour Index Number:
50040
Beilstein/REAXYS Number:
3918740
EC Number:
209-035-8
MDL number:
MFCD00012651
UNSPSC Code:
12171500
PubChem Substance ID:
329763896
NACRES:
MA.02

grade

for microscopy (Bact., Bot., Fl., Hist., Vit.)
indicator (pH 6.8-8.0)

Quality Level

100

form

powder or crystals

technique(s)

titration: suitable

pH

6.8-8.0, red to yellow

mp

290 °C (dec.) (lit.)

solubility

water: 0.01 g/10 mL

εmax

≥800 at 535-545 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Cl.CN(C)c1ccc2nc3cc(C)c(N)cc3nc2c1

InChI

1S/C15H16N4.ClH/c1-9-6-13-15(8-11(9)16)18-14-7-10(19(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H

InChI key

PGSADBUBUOPOJS-UHFFFAOYSA-N

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General description

Neutral red is a vital dye widely used as a cellular pH indicator and is selective for shifts in pH. It is highly lipophilic in nature. It favours membrane potential dependent fluorescence that attributes to changes in hydrophobicity.

Application

Neutral red has been used to stain mouse mammary glands.
Useful as an indicator for preparing neutral red paper, and as a biological stain.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCK5416
BCCH5901
BCCF1209
BCCD3079
BCCB9483

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John D Landua et al.
Journal of mammary gland biology and neoplasia, 14(4), 411-415 (2009-11-26)
Whole mount preparations of mouse mammary glands are useful for evaluating overall changes in growth and morphology, and are essential for detecting and evaluating focal or regionally-localized phenotypes that would be difficult to detect or analyze using other techniques. We
Sylvie V M Tesson et al.
Frontiers in microbiology, 9, 2681-2681 (2018-11-30)
Microalgae are common members of the atmospheric microbial assemblages. Diverse airborne microorganisms are known to produce ice nucleation active (INA) compounds, which catalyze cloud and rain formation, and thus alter cloud properties and their own deposition patterns. While the role
Ayesha Ali et al.
Cell reports, 30(5), 1463-1477 (2020-02-06)
The intact vaginal epithelium is essential for women's reproductive health and provides protection against HIV and sexually transmitted infections. How this epithelium maintains itself remains poorly understood. Here, we used single-cell RNA sequencing (RNA-seq) to define the diverse cell populations
Robim M Rodrigues et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 760-767 (2012-12-25)
When in vitro test systems are evaluated for assessment of the toxicity of chemical compounds, particular efforts are made to mimic the in vivo reality as close as possible. Cellular models with appropriate metabolic competence, i.e. with the potency to
Kun Guo et al.
Biosensors & bioelectronics, 47, 184-189 (2013-04-13)
This study introduces a novel and simple method to covalently graft neutral red (NR) onto carbon surfaces based on spontaneous reduction of in situ generated NR diazonium salts. Immobilization of neutral red on carbon surface was achieved by immersing carbon
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