ABE411

Anti-dimethyl Histone H3 (Arg26), Asymmetric Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: human
• técnicas: dot blot: suitable; immunocytochemistry: suitable; western blot: suitable
• Nº de acceso NCBI: NP_003520
• Nº de acceso UniProt: P68431
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: dimethylation (Arg26)
• Información sobre el gen: human ... HIST1H3F(8968)

Descripción

Descripción general

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Especificidad

Broad species reactivity is expected based on immunogen sequence similarities.

Aplicación

Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected dimethyl Histone H3 (Arg26), Asymmetric in A431 and HepG2 cells.

Dot Blot (Specificity) Analysis: 0.5 µg/mL from a representative lot detected dimethyl Histone H3 (Arg26), Asymmetric in Absurance Histone H3 Antibody Specificity Array (Cat. No. 16-667) and Absurance Histone H2A, H2B, H4 Antibody Specificity Array (Cat. No. 16-665).

DyLight is a registered trademark of Thermo Fisher Scientific.

This Anti-dimethyl Histone H3 (Arg26) antibody, Asymmetric is validated for use in western blotting, ICC & dot blot for the detection of dimethyl Histone H3 (Arg26).

Calidad

Evaluated by Western Blotting in untreated and CARM1 treated HeLa acid extracts.

Western Blotting Analysis: 1 µg/mL of this antibody detects dimethyl Histone H3 (Arg26), Asymmetric in 10 µg of CARM1 treated HeLa acid extract.

Descripción de destino

~17 kDa observed

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable