3570

Glicina

• Sinónimos: Glicocola, Ácido aminoacético, Ácido aminoetanoico
• Fórmula lineal: NH₂CH₂COOH
• Número de CAS: 56-40-6
• Peso molecular: 75.07
• Beilstein/REAXYS Number: 635782
• MDL number: MFCD00008131
• UNSPSC Code: 12352209
• NACRES: NA.54

Propiedades

• assay: >99% (by assay)
• Quality Level: 100
• form: crystalline solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• impurities: ≤100 CFU/g Total microorganism; ≤6.0 EU/g Endotoxin
• color: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• solubility: water: 250 mg/mL
• cation traces: Fe: ≤10 ppm; heavy metals (as Pb): ≤5 ppm
• shipped in: ambient
• storage temp.: 15-25°C
• SMILES string: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N

Descripción

General description

A non-essential, optically inactive, non-chiral amino acid. It is the smallest of the 20 natural amino acids. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons.

A nonpolar, uncharged amino acid.

Biochem/physiol Actions

Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Warning

Toxicity: Standard Handling (A)

Other Notes

Shapiro, S. 1997. Neurosurgery 40, 168.
Mount, H., et al. 1991. Mol. Pharmacol.39, 205.
Thompson, A.M., et al. 1989. Nature338, 422.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable