907383

Fmoc-L-Photo-Lysine

≥95%

• Sinónimos: N²-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N⁶-[[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine
• Fórmula empírica (notación de Hill): C₂₆H₃₀N₄O₆
• Número de CAS: 2250437-42-2
• Peso molecular: 494.54
• UNSPSC Code: 12352209

Propiedades

• assay: ≥95%
• form: solid
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-8°C

Descripción

Application

Fmoc-L-Photo-Lysine is a diazirine-containing, Fmoc-protected lysine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907251.

Other Notes

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable