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900862

Sigma-Aldrich

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

Sinónimos:

Hydroxyl diazirine TMS-alkyne, Probe building block

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About This Item

Fórmula empírica (notación de Hill):
C14H15F3N2OSi
Número de CAS:
2187374-13-4
Peso molecular:
312.36
Código UNSPSC:
12352200
NACRES:
NA.22

Ensayo

≥95%

Formulario

powder or crystals

temp. de almacenamiento

−20°C

cadena SMILES

OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C

Aplicación

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Otras notas

Technology Spotlight: Trifunctional Probe Building Blocks

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Referencia del producto
Descripción
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Hydroxyl di-benzophenone (PEG)3 alkyne

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3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine, ≥95%

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(4-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone HCl salt, ≥95%

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3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

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4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride

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4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid, ≥95%

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3-Amino-5-ethynylbenzenesulfonyl fluoride, ≥95%

900862

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

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3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

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4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900865

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907308

(3-(1,1-Difluoro-3-(triisopropylsilyl)prop-2-yn-1-yl)-3H-diazirin-3-yl)methanol, ≥95%

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Artículos

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

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