442631

Coumarin 6

98%

• Sinónimos: 3-(2-Benzothiazolyl)-7-(diethylamino)coumarin, 3-(2-Benzothiazolyl)-N,N-diethylumbelliferylamine
• Fórmula empírica (notación de Hill): C₂₀H₁₈N₂O₂S
• Número de CAS: 38215-36-0
• Peso molecular: 350.43
• Beilstein: 1085798
• Número CE: 253-830-2
• Número MDL: MFCD00041869
• Código UNSPSC: 12352103
• ID de la sustancia en PubChem: 24867935
• NACRES: NA.23

Propiedades

• Nivel de calidad: 100
• Ensayo: 98%
• Formulario: solid
• mp: 208-210 °C (lit.)
• λmáx.: 444 nm
• fluorescencia: λ_em 505 nm in ethanol (Lasing peak 534 nm, lasing range 515 - 558 nm (DMSO), pump source XeCl (308 nm))
• rendimiento de la unidad OLED: ITO/Alq₃:Coumarin 6/Mg:Ag;
  • Color: green
  • Max. EQE: 2.5 %
• cadena SMILES: CCN(CC)c1ccc2C=C(C(=O)Oc2c1)c3nc4ccccc4s3
• InChI: 1S/C20H18N2O2S/c1-3-22(4-2)14-10-9-13-11-15(20(23)24-17(13)12-14)19-21-16-7-5-6-8-18(16)25-19/h5-12H,3-4H2,1-2H3
• Clave InChI: VBVAVBCYMYWNOU-UHFFFAOYSA-N

Descripción

Descripción general

Coumarin 6 (C6) is a derivative of coumarin with a benzothiazolyl group at the position 3. It emits fluorescence in solid and solution state[1] and is used as fluorescent dye to stain organelles.[2] C6 is majorly used as blue-green spectrum laser dye and is microenvironment sensitive.[3]

Coumarin 6 is a fluorescent dye that belongs to the 7-diethylaminocoumarin series that can be used in a variety of biological activities. It can be used as a dopant that exhibits green light (500 nm) in optoelectronic applications.[4][5][6]

Aplicación

Coumarin 6 dye can be used in the labeling and visualization of polymeric nanoparticles in biological applications, such as oral drug delivery systems for cancer.[7] It can also be used in development of electroluminescent devices such as organic light emitting diodes (OLEDs).[8][9]

Coumarin 6 has been used as a hydrophobic fluorescent dye

• in block copolymer (BCP)-based micelle based drug delivery studies in glioma cell lines[10]
• in combination with flufenamic acid (FA) based nanoprodrug uptake in glioma cells[11]
• in poly(lactic-co-glycolic acid) (PLGA) based elvitegravir nanoprodrug uptake studies[12]

Laser dye

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)