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420247

Sigma-Aldrich

(+)-Borneol

97%

Sinónimos:

endo-(1R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

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About This Item

Fórmula empírica (notación de Hill):
C10H18O
Número de CAS:
464-43-7
Peso molecular:
154.25
Beilstein/REAXYS Number:
2038056
EC Number:
207-352-6
MDL number:
MFCD00066427
UNSPSC Code:
12352212
PubChem Substance ID:
24866321
NACRES:
NA.22

Quality Level

200

assay

97%

form

solid

optical activity

[α]20/D +36°, c = 5 in ethanol

mp

206-209 °C (lit.)

SMILES string

[H][C@@]12CC[C@@](C)([C@@H](O)C1)C2(C)C

InChI

1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1

InChI key

DTGKSKDOIYIVQL-WEDXCCLWSA-N

Gene Information

human ... UGT1A4(54657)

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General description

(+)-Borneol, a bicyclic monoterpene, is found in the essential oils of medicinal plants and is commonly used in traditional Chinese medicine for analgesia and anaesthesia.

Application

(+)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Flame
GHS02

signalword

Warning

hcodes

H228

Hazard Classifications

Flam. Sol. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 3

flash_point_f

149.0 °F - closed cup

flash_point_c

65 °C - closed cup

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.
Hur J, et al.
Pharmaceutical Analysis, 51(1), 30-35 (2013)
(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Jianyu Su et al.
Journal of food science, 77(6), C658-C664 (2012-05-16)
The aims of this study were to optimize the preparation conditions of natural borneol/β-cyclodextrin (NB/β-CD) inclusion complex by ultrasound method, and to investigate its improvement of stability and solubility. The complex was characterized by different various spectroscopic techniques including Fourier
Jing-yi Zhao et al.
Journal of Zhejiang University. Science. B, 13(12), 990-996 (2012-12-12)
Borneol, a monoterpenoid alcohol, is used widely, particularly in combined formulas for preventing and curing cardiovascular and cerebrovascular diseases in traditional Chinese medicine. In order to understand the blood and brain pharmacokinetics after intravenous, intranasal, or oral administration and to
Xiao Song et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(18), 2489-2492 (2012-01-20)
To investigate the absorption characteristic of borneol. Using single pass perfusion model, the active ingredient of borneol were detected by GC. The drug concentration, perfusion rate and pH value on the absorption of borneol were studied. Perfusion rate on the
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