The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
Synonym(s):
Caspase-8 Inhibitor I, Cell-Permeable, Granzyme B Inhibitor II, Cell-permeable, IETD-CHO, Cell-permeable
A potent, cell-permeable, and reversible inhibitor of caspase-8 and Granzyme B. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.
Potent, cell-permeable and reversible inhibitor of caspase-8 and Granzyme B.
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Hamada, E., et al. 1990. J. Hepatol. 30, 807.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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