SML1118

Hepcidin-25 (human) trifluoroacetate salt

≥95% (HPLC)

• Synonyme(s) : DTHFPICIFCCGCCHRSKCGMCCKT trifluoroacetate salt, H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH trifluoroacetate salt, Hepc25 (human), LEAP-1 (Liver-Expressed Antimicrobial Peptide) (human) trifluoroacetate salt, PLTR (Putative Liver Tumor Regressor ) (human)
• Formule empirique (notation de Hill): C₁₁₃H₁₇₀N₃₄O₃₁S₉ · xC₂HF₃O₂
• Numéro CAS: 342809-17-0
• Poids moléculaire : 2789.35 (free base basis)
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95% (HPLC)
• Forme: powder
• Couleur: white to off-white
• Conditions d'expédition: wet ice
• Température de stockage: −20°C

Description

Amino Acid Sequence

H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH trifluoroacetate salt

Actions biochimiques/physiologiques

Hepcidin is the master regulator of iron homeostasis. Hepcidin is found in liver, but also widely distributed in brain, where it may play a role in preventing iron-related neurodegeneration. Hepcidin has anti-inflammatory and antimicrobial activity.

Hepcidin-25 is the major isoform of hepcidin. hepcidin‐25 with reticulocyte hemoglobin content (CHr) in the hepcidin‐25 plot helps to differentiate DA can be differentiated iron‐deficient anemia (IDA) from the anemia of chronic disease (ACD) and the combined state of ACD/IDA. Mutation in the hepcidin gene is associated with the development of severe juvenile hemochromatosis.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable