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SMB01005

Sigma-Aldrich

Salvianolic acid B

≥85% (LC/MS-ELSD)

Synonyme(s) :

Lithospermic acid B, Salvianic acid B

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About This Item

Formule empirique (notation de Hill):
C36H30O16
Numéro CAS:
115939-25-8
Poids moléculaire :
718.61
Code UNSPSC :
12352205
Nomenclature NACRES :
NA.25

Source biologique

plant

Pureté

≥85% (LC/MS-ELSD)

Forme

solid

Poids mol.

718.61

Couleur

light yellow to brown

Solubilité

water: soluble

Application(s)

metabolomics
vitamins, nutraceuticals, and natural products

Température de stockage

−20°C

InChI

1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31-,32+/m1/s1

Clé InChI

SNKFFCBZYFGCQN-PDVBOLEISA-N

Description générale

Salvianolic acid B, also known as Lithospermic acid B, is a polyphenol and a member of catechols. This bioactive natural compound is commonly found in plants such as Salvia Sp., Isodon rubescens, Mentha Sp., Canna indica, and Angelica keiskei. Existing research suggests that this plant-derived natural product possesses a range of biological properties, including anticancer, anti-inflammatory, hepatoprotective, cardioprotective and neuroprotective activities.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Actions biochimiques/physiologiques

According to the existing research, Salvianolic acid B plays potential role in modulating inflammation, cell signaling, and immune responses by inhibiting the expression of COX, ERK, TNF-α, NO.
Salvianolic acid B has anti-obesity, antiviral (COVID-19) and free radical scavenging activity.

Caractéristiques et avantages

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Autres remarques

For additional information on our range of Biochemicals, please complete this form.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design
Almes F J, et al.
Computational Biology and Chemistry, 88, 107351-107351 (2020)
Lin Li et al.
Food & function, 11(10), 8743-8756 (2020-09-22)
Salvianolic acid B (Sal B) exhibits anti-obesity activity, yet the underlying mechanism linking this effect to metabolic endotoxemia remains unexplored. For this purpose, high-fat diet-induced obese mice were orally administered with Sal B for 10 weeks. Hematoxylin/eosin staining, transmission electron
Annarita Viggiano et al.
Applied and environmental microbiology, 84(4) (2017-12-03)
Chrysogine is a yellow pigment produced by Penicillium chrysogenum and other filamentous fungi. Although the pigment was first isolated in 1973, its biosynthetic pathway has so far not been resolved. Here, we show that deletion of the highly expressed nonribosomal

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