SAB5600047

Anti-BRAF (V600E) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM8, purified immunoglobulin

• Synonyme(s) : Anti-B-RAF1, Anti-B-raf, Anti-BRAF-1, Anti-BRAF1, Anti-NS7, Anti-RAFB1
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Produit recombinant: expressed in HEK 293 cells
• Niveau de qualité: 100
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: RM8, monoclonal; recombinant monoclonal
• Forme: buffered aqueous glycerol solution
• Espèces réactives: human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 0.5-2 μg/mL; immunoblotting: 0.5-2 μg/mL; immunocytochemistry: 0.5-5 μg/mL; immunohistochemistry: 0.5-5 μg/mL
• Isotype: IgG
• Numéro d'accès NCBI: 673
• Numéro d'accès UniProt: P15056
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... BRAF(673)

Description

Description générale

BRAF (B-Raf proto-oncogene) is a serine-threonine kinase, that codes for B-Raf protein. It is located on human chromosome 7q34.

Spécificité

This antibody reacts to the BRAF V600E mutant. No cross reactivity with wild type BRAF.

Immunogène

Peptide corresponding to BRAF V600E mutant

Actions biochimiques/physiologiques

BRAF (B-Raf proto-oncogene) participates in signaling direct cell growth. It induces tumor growth by initiating the mitogen-activated protein kinase (MAPK) pathway in various tumors like cutaneous melanoma and carcinomas of the thyroid and colon.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable