PLA0185

Rabbit anti-BRCA1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonyme(s) : BRCA1/BRCA2-containing complex, BRCAI, BRCC1, BROVCA1, FANCS, Fanconi anemia, IRIS, PNCA4, PPP1R53, PSCP, RING finger protein 53, RNF53, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, complementation group S, early onset, early onset breast cancer 1, protein phosphatase 1, regulatory subunit 53, subunit 1, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Qualité: Powered by Bethyl Laboratories, Inc.
• Espèces réactives: human
• Concentration: 1 mg/mL
• Technique(s): immunohistochemistry: 1:500- 1:2,000; immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:500- 1:2,500
• Numéro d'accès: NP_009225.1
• Numéro d'accès UniProt: P38398
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: rabbit ... BRCA1(672)

Description

Immunogène

The epitope recognized by PLA0185 maps to a region between residue 250 and 300 of human breast cancer 1 using the numbering given in entry NP_009225.1 (GeneID 672).

Forme physique

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Autres remarques

BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable