The stability of this product in corn oil has not been investigated. However, various external sources indicate that Estradiol benzoate may be stored in aliquots at -80°C for 2 years and -20°C for 1 year when prepared at 2.5 mg/mL or greater in a mixture of 1 part DMSO and 9 parts corn oil.
E8515
β-Estradiol 3-benzoate
≥97%
Synonyme(s) :
1,3,5(10)-estratriène-3,17β-diol 3-benzoate, 3,17β-dihydroxy-1,3,5(10)-estratriène 3-benzoate
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A propos de cet article
Formule empirique (notation de Hill) :
C25H28O3
Numéro CAS:
Poids moléculaire :
376.49
UNSPSC Code:
51111800
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-043-7
Beilstein/REAXYS Number:
3107526
MDL number:
Assay:
≥97%
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assay
≥97%
mp
191-198 °C (lit.)
SMILES string
[H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OC(=O)c5ccccc5)ccc24
InChI
1S/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1
InChI key
UYIFTLBWAOGQBI-BZDYCCQFSA-N
Application
β-Estradiol 3-benzoate has been used:to mimic estradiol in rat during the oestrous cycle in rats. It has also been used along with progesterone for the induction of sexual receptivity in female rat.[1]
Used in a study of general steroid metabolism and clearing, as groundwork for anabolic steroid screening in athletes.
Biochem/physiol Actions
β-Estradiol 3-benzoate is a synthetic estrogen. It favors breast cancer progression. It is an endocrine disrupting chemicals. It interacts with endocrine system and cause harmful effect on reproduction in animals and humans. It binds to estrogen receptors and favors tumor metastatis in breast, prostate and bone cells.
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Cet article | |||
|---|---|---|---|
| assay ≥97% | assay - | assay - | assay ≥98% (HPLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| mp 191-198 °C (lit.) | mp 176-180 °C (lit.) | mp 176-180 °C (lit.) | mp - |
signalword
Danger
hcodes
Hazard Classifications
Carc. 2 - Repr. 1B
Classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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If dissolved in corn oil, how is the stability? What is the recommended storage temperature and duration?
1 answer-
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How should stock solutions for the product β-Estradiol 3-benzoate (E8515) be stored?
1 answer-
Once the solution is prepared, it should be stored in separate packages to prevent product failure due to repeated freezing and thawing. The recommended storage period for the stock solution is as follows: when stored at -80°C, it should be used within 6 months; when stored at -20°C, it should be used within 1 month. To enhance solubility, the tube can be heated to 37°C and then agitated in an ultrasonic bath for a period of time.
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