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E1132

17β-Estradiol

ER agonist

Synonyme(s) :

1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin

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A propos de cet article

Formule empirique (notation de Hill) :
C18H24O2
Numéro CAS:
Poids moléculaire :
272.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352104
EC Number:
200-023-8
MDL number:
Beilstein/REAXYS Number:
1914275
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Nom du produit

β-Estradiol, analytical standard

grade

analytical standard

Quality Segment

packaging

vial of 250 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

176-180 °C (lit.)

application(s)

pharmaceutical

SMILES string

O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C

InChI

1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

InChI key

VOXZDWNPVJITMN-ZBRFXRBCSA-N

Biochem/physiol Actions

The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.
The major estrogen secreted by the premenopausal ovary.

Packaging

Supplied in amber screw-cap vials

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Cet article
E2758PHR1353K1001
description

analytical standard

description

BioReagent, powder, suitable for cell culture

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | mammalian: suitable, single cell analysis: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

application(s)

pharmaceutical

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

-

mp

176-180 °C (lit.)

mp

176-180 °C (lit.)

mp

176-180 °C (lit.)

mp

-

packaging

vial of 250 mg

packaging

-

packaging

-

packaging

-

grade

analytical standard

grade

-

grade

certified reference material, pharmaceutical secondary standard

grade

-


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pictograms

Health hazardEnvironment

signalword

Danger

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Classifications

Aquatic Chronic 1 - Carc. 2 - ED ENV 1 - ED HH 1 - Lact. - Repr. 1A



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Questions

  1. Can I just confirm that this product is water soluble, please? Thank you.

    1 answer
    1. The solubility of this product in water has not been determined. However, various sources report a solubility rate of 3.6 - 3.9 mg/L in water. Please see the link below to review these sources from PubChem:
      https://pubchem.ncbi.nlm.nih.gov/compound/Estradiol#section=Solubility

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