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53379

Sigma-Aldrich

FITC-CM-Dextran

average mol wt 40,000

Synonyme(s) :

FITC-CM-Dextran 40, Fluorescein isothiocyanate–Carboxymethyl–Dextran

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About This Item

Code UNSPSC :
12352108
Nomenclature NACRES :
NA.32

Source biologique

synthetic

Niveau de qualité

100

Conjugué

FITC conjugate

Forme

powder or crystals

Poids mol.

average mol wt 40,000

Composition

carboxymethyl content, 3-7%

Ampleur du marquage

0.001-0.020 mol/mol FITC glucose

Technique(s)

permeability assay: suitable

Fluorescence

λex 493 nm; λem 517 nm±5 nm in 0.1 M Tris pH 8.0

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Application

FITC-CM-Dextran 40, an anionic fluorescent dextran that may be used to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery. FITC-CM-Dextran 40 may be use to compare its selectivity versus neutral FITC-Dextran 40.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Vincent Yi-Fong Su et al.
Stem cells (Dayton, Ohio), 37(12), 1516-1527 (2019-10-08)
Induced pluripotent stem cells (iPSCs) can reduce the severity of endotoxin-induced acute lung injury (ALI). However, the interaction between iPSCs and vascular endothelium remains unclear. In this study, we investigated the effects of iPSCs in moderating pulmonary endothelial leakage in
Rui Liu et al.
International journal of molecular medicine, 42(5), 2903-2913 (2018-08-23)
Inflammatory bowel disease (IBD) is a multifactorial inflammatory disease, and increasing evidence has demonstrated that the mechanism of the pathogenesis of IBD is associated with intestinal epithelial barrier injury. Long non‑coding RNAs (lncRNAs) are a class of transcripts >200 nucleotides
Chichi Li et al.
Cell death & disease, 10(11), 804-804 (2019-10-28)
Adipose-derived stem cells (ADSCs) have been shown to be beneficial in some pulmonary diseases, and the paracrine effect is the major mechanism underlying ADSC-based therapy. Autophagy plays a crucial role in maintaining stem cell homeostasis and survival. However, the role
Dan Zhang et al.
Journal of cellular physiology, 233(1), 688-698 (2017-03-23)
Understanding the role and underlying regulation mechanism of autophagy in lipopolysaccharide-induced lung injury (LPS-LI) may provide potentially new pharmacological targets for treatment of acute lung injury. The aim of this study was to investigate the functional significance of autophagy in
Carrier and dose effects on the pharmacokinetics of T-0128, a camptothecin analogue-carboxymethyl dextran conjugate, in non-tumor- and tumor-bearing rats.
Harada M, Murata J, Sakamura Y, et al.
J. Controlled Release, 71, 71-86 (2001)
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