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C1425000

Chloramphenicol sodium succinate

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Chloramphenicol succinate sodium salt, Chloramphenicol α-succinate

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About This Item

Formule linéaire :
C15H15Cl2N2O8Na
Numéro CAS:
982-57-0
Poids moléculaire :
445.18
Numéro MDL:
MFCD00079025
Code UNSPSC :
41116107
ID de substance PubChem :
329774883
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

chloramphenicol

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

[Na].O[C@@H]([C@@H](COC(=O)CCC(O)=O)NC(=O)C(Cl)Cl)c1ccc(cc1)N(=O)=O

InChI

1S/C15H16Cl2N2O8.Na.H/c16-14(17)15(24)18-10(7-27-12(22)6-5-11(20)21)13(23)8-1-3-9(4-2-8)19(25)26;;/h1-4,10,13-14,23H,5-7H2,(H,18,24)(H,20,21);;/t10-,13-;;/m1../s1

Clé InChI

RJOAHMNSYANTPN-OWVUFADGSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chloramphenicol sodium succinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

C1200000

Chloramphénicol, European Pharmacopoeia (EP) Reference Standard

C1400000

Chloramphenicol palmitate isomer, European Pharmacopoeia (EP) Reference Standard

C1300000

Chloramphenicol dipalmitate, European Pharmacopoeia (EP) Reference Standard

C1350000

Chloramphenicol disodium disuccinate, European Pharmacopoeia (EP) Reference Standard

PHR1412

Chloramphenicol, Pharmaceutical Secondary Standard; Certified Reference Material

1107004

Chloramphénicol, United States Pharmacopeia (USP) Reference Standard

1107300

Chloramphenicol palmitate, United States Pharmacopeia (USP) Reference Standard

1107401

Chloramphenicol palmitate, United States Pharmacopeia (USP) Reference Standard

1107503

Chloramphenicol palmitate, United States Pharmacopeia (USP) Reference Standard

BP854

Chloramphénicol, British Pharmacopoeia (BP) Reference Standard

BP1061

Chloramphenicol sodium succinate, British Pharmacopoeia (BP) Reference Standard

BP417

2-Amino-1-(4-nitrophenyl)propane-1,3-diol, British Pharmacopoeia (BP) Reference Standard

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H351

Classification des risques

Acute Tox. 4 Oral - Carc. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

C S Ambekar et al.
Toxicology in vitro : an international journal published in association with BIBRA, 18(4), 441-447 (2004-05-08)
From our previous study [Eur. J. Clin. Pharmacol. 56 (2000) 405] we hypothesized that chloramphenicol succinate (CAPS) may be a competitive substrate for succinate dehydrogenase (SDH). It may be oxidized by SDH to release chloramphenicol (CAP), which may inhibit SDH
Janet I Ejiofor et al.
Canadian journal of physiology and pharmacology, 85(6), 582-587 (2007-09-08)
Artemether (AM), a highly effective treatment for multidrug-resistant malaria and a component of artemisinin combination therapy, has been associated with some neurotoxicity following repeated high doses. This study was aimed at investigating the effect of AM on pentobarbitone sleep and
J A Turton et al.
Human & experimental toxicology, 18(9), 566-576 (1999-10-19)
1. Chloramphenicol has been widely used in the treatment of serious infections including typhoid fever and meningitis. However, the drug is haemotoxic in man inducing firstly, a reversible, dose-dependent anaemia which develops during treatment, secondly, an often fatal aplastic anaemia
M Ashton et al.
European journal of clinical pharmacology, 45(2), 181-186 (1993-01-01)
The disposition of chloramphenicol and chloramphenicol monosuccinate has been studied in thirty-four Ethiopian children of varying nutritional status. After a single intravenous dose corresponding to chloramphenicol 25 mg per kg bodyweight, the plasma clearance of chloramphenicol monosuccinate was decreased only
Treatment of severe typhoid fever in children with high dose dexamethasone.
N H Punjabi et al.
The Pediatric infectious disease journal, 7(8), 598-600 (1988-08-01)
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